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胃切除术后的胃癌

Gastric cancer after gastrectomy.

作者信息

Arnthorsson G, Tulinius H, Egilsson V, Sigvaldason H, Magnusson B, Thorarinsson H

机构信息

Department of Surgery, University of Iceland, Reykjavík.

出版信息

Int J Cancer. 1988 Sep 15;42(3):365-7. doi: 10.1002/ijc.2910420310.

Abstract

Inhabitants of Iceland who had undergone gastric resection for non-malignant diseases between 1930 and 1974 were identified and followed up at the Icelandic Cancer Registry in order to evaluate the risk of gastric cancer subsequent to gastric resection. There were 1,214 males and 581 females, contributing 30,792 person/years. The results show an overall 1.16-fold, not significant, increase in the relative risk for gastric cancer. In the first 15 years after operation the risk was decreased, 0.49, 95% confidence interval (CI) 0.24-0.90, but from 15 years or more following operation, the risk was 2.17, 95% CI 1.46-3.10. We conclude that for these subjects the risk is not significantly increased. Patients surviving 15 years or more after operation have an increased risk (p less than 0.001), but they do not contribute substantially to the number of gastric cancer patients in Iceland.

摘要

我们确定了1930年至1974年间因非恶性疾病接受胃切除术的冰岛居民,并在冰岛癌症登记处对他们进行了随访,以评估胃切除术后患胃癌的风险。其中男性1214人,女性581人,共随访30792人年。结果显示,胃癌相对风险总体增加了1.16倍,但差异无统计学意义。术后前15年风险降低,相对风险为0.49,95%置信区间(CI)为0.24 - 0.90,但术后15年及更长时间,相对风险为2.17,95%CI为1.46 - 3.10。我们得出结论,对于这些受试者,风险没有显著增加。术后存活15年及以上的患者风险增加(p < 0.001),但他们对冰岛胃癌患者数量的贡献不大。

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