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2019年冠状病毒病大流行对全球抗菌药物和消毒剂耐药性的潜在影响:抗菌药物耐药性洞察全球视角

The potential impact of the COVID-19 pandemic on global antimicrobial and biocide resistance: an AMR Insights global perspective.

作者信息

Ansari Shamshul, Hays John P, Kemp Andrew, Okechukwu Raymond, Murugaiyan Jayaseelan, Ekwanzala Mutshiene Deogratias, Ruiz Alvarez Maria Josefina, Paul-Satyaseela Maneesh, Iwu Chidozie Declan, Balleste-Delpierre Clara, Septimus Ed, Mugisha Lawrence, Fadare Joseph, Chaudhuri Susmita, Chibabhai Vindana, Wadanamby J M Rohini W W, Daoud Ziad, Xiao Yonghong, Parkunan Thulasiraman, Khalaf Yara, M'Ikanatha Nkuchia M, van Dongen Maarten B M

机构信息

Department of Microbiology, Chitwan Medical College and Teaching Hospital, Bharatpur, 44200 Chitwan, Nepal.

Department of Medical Microbiology & Infectious Diseases, Erasmus University Medical Centre Rotterdam (Erasmus MC), Rotterdam, The Netherlands.

出版信息

JAC Antimicrob Resist. 2021 Apr 8;3(2):dlab038. doi: 10.1093/jacamr/dlab038. eCollection 2021 Jun.

Abstract

The COVID-19 pandemic presents a serious public health challenge in all countries. However, repercussions of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections on future global health are still being investigated, including the pandemic's potential effect on the emergence and spread of global antimicrobial resistance (AMR). Critically ill COVID-19 patients may develop severe complications, which may predispose patients to infection with nosocomial bacterial and/or fungal pathogens, requiring the extensive use of antibiotics. However, antibiotics may also be inappropriately used in milder cases of COVID-19 infection. Further, concerns such as increased biocide use, antimicrobial stewardship/infection control, AMR awareness, the need for diagnostics (including rapid and point-of-care diagnostics) and the usefulness of vaccination could all be components shaping the influence of the COVID-19 pandemic. In this publication, the authors present a brief overview of the COVID-19 pandemic and associated issues that could influence the pandemic's effect on global AMR.

摘要

新冠疫情给所有国家带来了严峻的公共卫生挑战。然而,严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染对未来全球健康的影响仍在调查中,包括该疫情对全球抗菌药物耐药性(AMR)出现和传播的潜在影响。危重新冠肺炎患者可能会出现严重并发症,这可能使患者易感染医院内的细菌和/或真菌病原体,从而需要大量使用抗生素。然而,在症状较轻的新冠病毒感染病例中,抗生素也可能被不恰当地使用。此外,诸如增加消毒剂使用、抗菌药物管理/感染控制、AMR意识、诊断需求(包括快速和即时诊断)以及疫苗接种的有效性等问题,都可能是塑造新冠疫情影响的因素。在本出版物中,作者简要概述了新冠疫情以及可能影响该疫情对全球AMR影响的相关问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9786/8210252/3b4647d03abb/dlab038f1.jpg

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