Coppen A, Gupta R, Montgomery S, Ghose K, Bailey J, Burns B, de Ridder J J
Br J Psychiatry. 1976 Oct;129:342-5. doi: 10.1192/bjp.129.4.342.
The antidepressant activities of mianserin hydrochloride were investigated and compared with those of amitriptyline. The therapeutic efficacy of the two drugs appeared similar, but the incidence of side-effects was significantly higher with amitriptyline. Plasma levels of mianserin were determined during the trial and were not related to the therapeutic activity of the drug.
对盐酸米安色林的抗抑郁活性进行了研究,并与阿米替林的抗抑郁活性进行了比较。两种药物的治疗效果似乎相似,但阿米替林的副作用发生率明显更高。在试验期间测定了米安色林的血浆水平,其与该药物的治疗活性无关。