Busso Dolores, David Andrea, Penailillo Reyna, Echeverría Guadalupe, Rigotti Attilio, Kovalskys Irina, Gómez Georgina, Cortés Sanabria Lilia Yadira, Yépez García Martha Cecilia, Pareja Rossina G, Herrera-Cuenca Marianella, Fisberg Mauro
Biomedical Research and Innovation Center, School of Medicine, Universidad de los Andes, Santiago 7550000, Chile.
Department of Nutrition, Diabetes and Metabolism, School of Medicine, Pontificia Universidad Católica de Chile, Santiago 8320000, Chile.
Nutrients. 2021 Jun 7;13(6):1954. doi: 10.3390/nu13061954.
Vitamin E was identified as a lipophilic compound essential to maintain rat pregnancy. Low vitamin E intake during early pregnancy associates with congenital malformations and embryonic loss in animals and with miscarriage and intrauterine growth restriction in humans. Vitamin E protects cell membranes from lipoperoxidation and exerts non-antioxidant activities. Its function can be restored by vitamin C; thus, intake and circulating levels of both micronutrients are frequently analyzed together. Although substantial vitamin E inadequacy was reported worldwide, its consumption in Latin America (LatAm) is mostly unknown. Using data from the Latin American Study of Nutrition and Health (, ELANS), we evaluated vitamin E and C intake in women of reproductive age (WRA) from eight LatAm countries and identified their main food sources. Two non-consecutive 24-h dietary recalls in 3704 women aged from 15 to 49 years and living in urban locations showed low average intake of vitamin E (7.9 mg/day vs. estimated average requirement (EAR) of 12 mg/day) and adequate overall vitamin C consumption (95.5 mg/day vs. EAR of 60 mg/day). The mean regional inadequacy was 89.6% for vitamin E and 36.3% for vitamin C. The primary food sources of vitamin E were fats and oils, as well as vegetables. Vitamin C intake was explained mainly by the consumption of fruit juices, fruits, and vegetables. Combined deficient intake of both vitamins was observed in 33.7% of LatAm women. Although the implications of low antioxidant vitamins' consumption in WRA are still unclear, the combined deficient intake of both vitamins observed in one-third of ELANS participants underscores the need for further research on this topic.
维生素E被确定为维持大鼠妊娠所必需的亲脂性化合物。妊娠早期维生素E摄入量低与动物的先天性畸形和胚胎丢失以及人类的流产和宫内生长受限有关。维生素E可保护细胞膜免受脂质过氧化作用，并发挥非抗氧化活性。其功能可通过维生素C恢复；因此，这两种微量营养素的摄入量和循环水平经常一起分析。尽管全球范围内都报告了维生素E严重不足的情况，但拉丁美洲（拉美）的维生素E消费量大多未知。利用拉丁美洲营养与健康研究（ELANS）的数据，我们评估了来自拉美八个国家的育龄妇女（WRA）的维生素E和C摄入量，并确定了她们的主要食物来源。对3704名年龄在15至49岁、居住在城市地区的妇女进行的两次非连续24小时饮食回忆显示，维生素E的平均摄入量较低（7.9毫克/天，而估计平均需求量（EAR）为12毫克/天），而维生素C的总体消费量充足（95.5毫克/天，而EAR为60毫克/天）。维生素E的平均区域不足率为89.6%，维生素C为36.3%。维生素E的主要食物来源是油脂以及蔬菜。维生素C的摄入量主要由果汁、水果和蔬菜的消费来解释。33.7%的拉美妇女同时存在两种维生素摄入不足的情况。尽管育龄妇女低抗氧化维生素消费量的影响仍不明确，但在三分之一的ELANS参与者中观察到的两种维生素同时摄入不足的情况凸显了对该主题进行进一步研究的必要性。
