Vamanu Emanuel, Dinu Laura Dorina, Pelinescu Diana Roxana, Gatea Florentina
Faculty of Biotechnology, University of Agronomic Science and Veterinary Medicine, 59 Marasti Blvd, 1 District, 011464 Bucharest, Romania.
Department of Genetics, University of Bucharest, 36-46 Bd. M. Kogalniceanu, 5th District, 050107 Bucharest, Romania.
Microorganisms. 2021 Jun 10;9(6):1262. doi: 10.3390/microorganisms9061262.
Edible mushrooms are functional foods and valuable but less exploited sources of biologically active compounds. Herbal teas are a range of products widely used due to the therapeutic properties that have been demonstrated by traditional medicine and a supplement in conventional therapies. Their interaction with the human microbiota is an aspect that must be researched, the therapeutic properties depending on the interaction with the microbiota and the consequent fermentative activity. Modulation processes result from the activity of, for example, phenolic acids, which are a major component and which have already demonstrated activity in combating oxidative stress. The aim of this mini-review is to highlight the essential aspects of modulating the microbiota using edible mushrooms and herbal teas. Although the phenolic pattern is different for edible mushrooms and herbal teas, certain non-phenolic compounds (polysaccharides and/or caffeine) are important in alleviating chronic diseases. These specific functional compounds have modulatory properties against oxidative stress, demonstrating health-beneficial effects in vitro and/or In vivo. Moreover, recent advances in improving human health via gut microbiota are presented. Plant-derived miRNAs from mushrooms and herbal teas were highlighted as a potential strategy for new therapeutic effects.
可食用蘑菇是功能性食品，也是具有生物活性化合物的宝贵但未得到充分开发的来源。草药茶是一系列因传统医学已证明的治疗特性而被广泛使用的产品，也是传统疗法中的一种补充剂。它们与人体微生物群的相互作用是一个必须研究的方面，其治疗特性取决于与微生物群的相互作用以及随之而来的发酵活性。调节过程源于例如酚酸的活性，酚酸是主要成分，并且已经证明其在对抗氧化应激方面具有活性。本综述的目的是强调使用可食用蘑菇和草药茶调节微生物群的重要方面。尽管可食用蘑菇和草药茶的酚类模式不同，但某些非酚类化合物（多糖和/或咖啡因）在缓解慢性病方面很重要。这些特定的功能性化合物具有对抗氧化应激的调节特性，在体外和/或体内显示出对健康有益的效果。此外，还介绍了通过肠道微生物群改善人类健康的最新进展。来自蘑菇和草药茶的植物源微小RNA被强调为产生新治疗效果的潜在策略。
