CLIMB-COVID：支持 SARS-CoV-2 基因组监测的去中心化测序的持续集成。
CLIMB-COVID: continuous integration supporting decentralised sequencing for SARS-CoV-2 genomic surveillance.
机构信息
Institute of Microbiology and Infection, University of Birmingham, Birmingham, UK.
Pathogen Genomics Unit, Public Health Wales NHS Trust, Cardiff, UK.
出版信息
Genome Biol. 2021 Jul 1;22(1):196. doi: 10.1186/s13059-021-02395-y.
In response to the ongoing SARS-CoV-2 pandemic in the UK, the COVID-19 Genomics UK (COG-UK) consortium was formed to rapidly sequence SARS-CoV-2 genomes as part of a national-scale genomic surveillance strategy. The network consists of universities, academic institutes, regional sequencing centres and the four UK Public Health Agencies. We describe the development and deployment of CLIMB-COVID, an encompassing digital infrastructure to address the challenge of collecting and integrating both genomic sequencing data and sample-associated metadata produced across the COG-UK network.
针对英国目前正在发生的 SARS-CoV-2 疫情，COVID-19 英国基因组学联盟（COG-UK）成立，目的是对 SARS-CoV-2 基因组进行快速测序，作为国家规模基因组监测策略的一部分。该网络由大学、学术机构、区域测序中心和四个英国公共卫生机构组成。我们描述了 CLIMB-COVID 的开发和部署，这是一种全面的数字基础设施，用于解决在 COG-UK 网络中收集和整合基因组测序数据和样本相关元数据的挑战。
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