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氟化物和亚锡离子包埋的混合涂层对牙齿腐蚀性磨损的抑制作用。

Erosive tooth wear inhibition by hybrid coatings with encapsulated fluoride and stannous ions.

机构信息

Department of Restorative Dentistry, University of São Paulo, School of Dentistry, São Paulo, São Paulo, Brazil.

Department of Chemical Engineering, Polytechnic School, São Paulo University-USP, São Paulo, São Paulo, Brazil.

出版信息

J Mater Sci Mater Med. 2021 Jul 1;32(7):83. doi: 10.1007/s10856-021-06554-2.

Abstract

This study aimed to formulate a hybrid coating material (HC) and to modify this HC with fluoride (NaF) and stannous (SnCl) ions, directly or encapsulated in nano containers, testing the effects of these materials against dental erosion and erosion-abrasion. Enamel and dentin specimens were treated with the HCs, and then tested in erosion or erosion-abrasion cycling models of 5 days (n = 10 for each substrate, for each model). Deionized water was the negative control, and a fluoride varnish, the positive control. Surface loss (SL, in µm) was evaluated with an optical profilometer, and data were statistically analyzed (α = 0.05). For enamel, in erosion, the positive control and HC without additives showed significantly lower SL than the negative control (p = 0.003 and p = 0.001). In erosion-abrasion, none of the groups differed from the negative control (p > 0.05). For dentin, in erosion, the positive control, HC without additives, HC with non-encapsulated F, and HC with encapsulated F + Sn showed lower SL than the negative control (p < 0.05). In erosion-abrasion, none of the groups differed significantly from the negative control (p < 0.05). HC without additives showed a promising potential for protecting the teeth against dental erosion (with upward trend for improved protection on dentin), but not against erosion-abrasion. The presence of additives did not improve the protective effect of the HC, on both substrates.

摘要

本研究旨在制备一种混合涂层材料(HC),并通过直接或封装在纳米容器中添加氟化物(NaF)和亚锡(SnCl)离子来修饰这种 HC,以测试这些材料对牙齿酸蚀和酸蚀磨损的影响。用 HC 处理牙釉质和牙本质标本,然后在 5 天的酸蚀或酸蚀磨损循环模型中进行测试(每种基质,每种模型各有 10 个样本)。去离子水为阴性对照,氟化物涂料为阳性对照。用光学轮廓仪评估表面损失(SL,以 µm 计),并进行统计分析(α=0.05)。对于牙釉质,在酸蚀中,阳性对照和未添加添加剂的 HC 的 SL 明显低于阴性对照(p=0.003 和 p=0.001)。在酸蚀磨损中,与阴性对照相比,没有任何一组有差异(p>0.05)。对于牙本质,在酸蚀中,阳性对照、未添加添加剂的 HC、未封装 F 的 HC 和封装 F+Sn 的 HC 的 SL 均低于阴性对照(p<0.05)。在酸蚀磨损中,与阴性对照相比,没有任何一组有显著差异(p<0.05)。未添加添加剂的 HC 具有保护牙齿免受酸蚀的潜力(对牙本质的保护作用呈上升趋势),但对酸蚀磨损的保护作用则不然。添加剂的存在并没有提高 HC 的保护效果,在两种基质上都是如此。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17b2/8249257/1031c472d09b/10856_2021_6554_Fig1_HTML.jpg

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