Barnes G L, Vaelioja L, McShane S
Department of Gastroenterology, Royal Children's Hospital, Parkville, Victoria, Australia.
Aust Paediatr J. 1988 Jun;24(3):191-3. doi: 10.1111/j.1440-1754.1988.tb00323.x.
A new method of collecting and analysing sweat (Wescor Macroduct) has advantages of simplicity of collection and direct reading of results by osmometry. Forty-seven children with cystic fibrosis and 47 normal children had sweat tests performed simultaneously by the Gibson and Cooke method and by the Wescor Macroduct method. The new method had a higher rate of inadequate collection (19% vs 6%) which was more marked in children under 5 years of age. This was due partly to the difficulty of fitting a 2.5 cm pilocarpine gel disc to small arms. When an adequate collection was obtained, results were reliable with no false negatives occurring during this study. The Wescor Macroduct sweat test is a reliable method for use in peripheral centres to screen patients suspected of having cystic fibrosis. All children with an inadequate collection or a positive result should be referred to a reference centre for confirmation of the diagnosis. However, the majority will be saved the expense and disruption of travel.
一种收集和分析汗液的新方法（伟思高微量导管法）具有收集简便且可通过渗透压测定法直接读取结果的优点。47名囊性纤维化患儿和47名正常儿童同时采用吉布森和库克方法以及伟思高微量导管法进行了汗液测试。新方法的收集不足率较高（19%对6%），在5岁以下儿童中更为明显。部分原因是将2.5厘米的毛果芸香碱凝胶盘贴在小手臂上存在困难。当获得足够的汗液收集量时，结果可靠，在本研究期间未出现假阴性。伟思高微量导管汗液测试是一种可靠的方法，可用于基层医疗中心筛查疑似患有囊性纤维化的患者。所有收集不足或结果呈阳性的儿童都应转诊至参考中心以确诊。然而，大多数人将节省旅行费用和不便。
