Carter E P, Barrett A D, Heeley A F, Kuzemko J A
Arch Dis Child. 1984 Oct;59(10):919-22. doi: 10.1136/adc.59.10.919.
We describe a new technique of collecting sweat for measurement of osmolality and sodium concentrations. Eighty two subjects were studied--39 controls and 43 patients with cystic fibrosis. Adequate amounts of sweat were obtained in 81 subjects and sweat was analysed for both osmolality and sodium concentrations in 73 subjects. The 34 controls gave sweat osmolality and sodium values ranging from 62 to 196 mmol/kg and 9 to 72 mmol/l respectively. The 39 cystic fibrosis patients gave osmolality values ranging from 220 to 416 mmol/kg and sodium concentrations ranging from 60 to 150 mmol/l. Sweat osmolality alone was determined in eight infants under 50 days of age--four later developed the clinical features of cystic fibrosis and four, in whom cystic fibrosis was suspected, were later excluded. Sweat osmolality values in these two groups ranged from 255 to 345 mmol/kg and 87 to 123 mmol/kg respectively. The simplicity of collecting sweat and the measurement of osmolality offer distinct advantages over techniques previously described.
我们描述了一种收集汗液以测量渗透压和钠浓度的新技术。研究了82名受试者，其中39名对照者和43名囊性纤维化患者。81名受试者获得了足够量的汗液，73名受试者的汗液进行了渗透压和钠浓度分析。34名对照者的汗液渗透压和钠值分别为62至196 mmol/kg和9至72 mmol/l。39名囊性纤维化患者的渗透压值为220至416 mmol/kg，钠浓度为60至150 mmol/l。单独测定了8名50日龄以下婴儿的汗液渗透压，其中4名后来出现了囊性纤维化的临床特征，4名疑似患有囊性纤维化的婴儿后来被排除。这两组婴儿的汗液渗透压值分别为255至345 mmol/kg和87至123 mmol/kg。与先前描述的技术相比，收集汗液和测量渗透压的简单性具有明显优势。
