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通过对食盐进行四重强化,向弱势群体提供铁、碘、叶酸和维生素B。

Quadruple fortification of salt for the delivery of iron, iodine, folic acid, and vitamin B to vulnerable populations.

作者信息

Modupe Oluwasegun, Diosady Levente L

机构信息

Department of Chemical Engineering and Applied Chemistry, University of Toronto, Canada.

出版信息

J Food Eng. 2021 Jul;300:110525. doi: 10.1016/j.jfoodeng.2021.110525.

DOI:10.1016/j.jfoodeng.2021.110525
PMID:34219855
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7985676/
Abstract

A process for simultaneous delivery of iron, iodine, folic acid, and vitamin B through salt as a potential and holistic approach to ameliorate anaemia and reduce maternal and infant mortality is presented. Two approaches for adding folic acid and B to salt during double fortification with iron and iodine were investigated. Attempts to add both micronutrients through the iodine spray solution were unsuccessful. Hence, folic acid was added through a stabilized iodine solution, and B was added through the iron premix. Four approaches used to incorporate B into the iron premix were investigated: (1) co-extruding B with iron, (2) spraying B on the surface of the iron extrudate, (3) adding B to the colour masking agent, and (4) adding B to the outer coating. Of these approaches, coextrusion (1) was the best, based on the ease of production and stability of fortificants. The salt formulated with the solid iron-B premix and sprayed iodine and folic acid solution contained 1000 ppm iron, 50 ppm iodine, 25 ppm folic acid, and 0.25 ppm B. Over 98% of B, 93% folic acid, and 94% iodine were retained after 6-month storage in the best formulation. This technology can simultaneously deliver iron, iodine, folic acid, and vitamin B in a safe and stable salt enabling public health measures for improved health at a minimal additional cost.

摘要

本文介绍了一种通过食盐同时输送铁、碘、叶酸和维生素B的方法,作为改善贫血以及降低母婴死亡率的一种潜在的整体方法。研究了在铁和碘双重强化过程中向食盐中添加叶酸和维生素B的两种方法。尝试通过碘喷雾溶液添加这两种微量营养素均未成功。因此,通过稳定化碘溶液添加叶酸,通过铁预混料添加维生素B。研究了将维生素B加入铁预混料的四种方法:(1)将维生素B与铁共挤出,(2)将维生素B喷洒在铁挤出物表面,(3)将维生素B加入颜色掩蔽剂中,(4)将维生素B加入外涂层中。基于生产的简易性和强化剂的稳定性,这些方法中,共挤出法(1)是最佳方法。用固体铁-维生素B预混料、喷洒碘和叶酸溶液配制的食盐含有1000 ppm的铁、50 ppm的碘、25 ppm的叶酸和0.25 ppm的维生素B。在最佳配方中储存6个月后,超过98%的维生素B、93%的叶酸和94%的碘得以保留。该技术可以在安全稳定的食盐中同时输送铁、碘、叶酸和维生素B,以最低的额外成本实现改善健康状况的公共卫生措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/d6e493830a71/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/ea41602c7c4c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/32edf3236580/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/21e0f172e973/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/58805875e017/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/3edfd530af59/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/d6e493830a71/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/ea41602c7c4c/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/32edf3236580/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/21e0f172e973/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/58805875e017/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/3edfd530af59/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c84f/7985676/d6e493830a71/gr6.jpg

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