Witte W, Braulke C
Institut für Experimentelle Epidemiologie, German Democratic Republic.
Epidemiol Infect. 1987 Dec;99(3):603-12. doi: 10.1017/s0950268800066450.
Multiply- and methicillin-resistant Staphylococcus aureus (MRSA) strains have been isolated from five small outbreaks of nosocomial infection in five different hospitals. The MRSA were typed by phage patterns, biochemical traits, resistance phenotypes and plasmid patterns. Three different groups of strains can be distinguished. The MRSA from three outbreaks in one country share identical characters. Phage typing by the use of the International Basic Set for Phage Typing staphylococci as well as experimental phages does not completely discriminate between the strains. Attribution of several resistance determinants to plasmids in two of the described strain groups proved valuable for strain differentiation. These multiply-resistant strains are sensitive to vancomycin and to rifampicin.
多重耐药及耐甲氧西林金黄色葡萄球菌（MRSA）菌株已从五家不同医院的五起医院感染小暴发中分离出来。通过噬菌体分型、生化特性、耐药表型和质粒图谱对MRSA进行分型。可区分出三组不同的菌株。来自一个国家三起暴发的MRSA具有相同特征。使用国际葡萄球菌噬菌体分型基本集以及实验性噬菌体进行噬菌体分型并不能完全区分这些菌株。在所描述的两组菌株中，将几种耐药决定因素归因于质粒对菌株鉴别很有价值。这些多重耐药菌株对万古霉素和利福平敏感。
