Morimoto A, Watanabe T, Myogin T, Murakami N
Department of Physiology, Yamaguchi University School of Medicine, Ube, Japan.
Pflugers Arch. 1987 Nov;410(4-5):554-6. doi: 10.1007/BF00586538.
We investigated whether a restraint induced stress elicits an acute-phase response which includes changes in the plasma trace metals, fibrinogen and the circulating leucocyte count. The present results showed that restraint-stress induces significant increases in the plasma concentrations of copper and fibrinogen and decreases in those of iron and zinc in rabbits, indicating that some of acute-phase response are produced without fever mediated by endogenous pyrogen.
