Alhazmi Lenah Sulaiman S, Bawadood Manar Abubaker A, Aljohani Alhasan Mohammad S, Alzahrani Abdulmajeed Abdullah R, Moshref Leena, Trabulsi Nora, Moshref Rana
General Surgery, King Abdulaziz University, Jeddah, SAU.
Cureus. 2021 Jun 28;13(6):e15994. doi: 10.7759/cureus.15994. eCollection 2021 Jun.
Pain is a significant problem and is one of the most invalidating symptoms in breast cancer (BC) patients that would negatively affect the functional status and the Quality of Life (QoL). Pain management in BC patients requires thorough patient evaluation and critical assessment of pain. The actual cause for the pain must be recognized, so management can be tailored to each patient. This review aims to discuss various treatment modalities employed for effectively managing pain in BC patients. Pharmacotherapy makes up the cornerstone of the management of pain in BC patients. Both opioid and non-opioid analgesics are utilized. The WHO recommends a method called "by the ladder" for managing pain in BC patients where analgesics are used in ascending order. In comprehensive pain management (CPM), non-pharmacologic therapies are gaining wide acceptance and popularity, including complementary and alternative medicine (CAM), procedural and psychosocial interventions. Procedural interventions are usually used in case of severe pain refractory to pharmacological therapy. Techniques, such as radiotherapy, neurectomy, and nerve blocks, are effective in managing cancer pain. However, CAM therapies in BC pain management need to be guided by enough scientific evidence, decision-making, and medical judgment of regulatory bodies. BC pain management is based on careful routine pain assessments and appropriate patient evaluation both physically and psychologically. Pain control is one of the methods to improve the QoL of BC patients. Both pharmacological and non-pharmacological therapies are accessible to patients today, but they should be used with caution to minimize toxicity and increase effectiveness. The use of any pain management intervention should be based on proper scientific evidence and collective medical judgment.
疼痛是一个重要问题,是乳腺癌(BC)患者中最使人丧失活动能力的症状之一,会对功能状态和生活质量(QoL)产生负面影响。BC患者的疼痛管理需要对患者进行全面评估并对疼痛进行严格评估。必须识别疼痛的实际原因,以便针对每个患者制定管理方案。本综述旨在讨论用于有效管理BC患者疼痛的各种治疗方式。药物治疗是BC患者疼痛管理的基石。阿片类和非阿片类镇痛药均有使用。世界卫生组织推荐一种名为“按阶梯”的方法来管理BC患者的疼痛,即按升序使用镇痛药。在综合疼痛管理(CPM)中,非药物疗法正获得广泛认可和普及,包括补充和替代医学(CAM)、程序性和心理社会干预。程序性干预通常用于药物治疗难以缓解的严重疼痛情况。放疗、神经切除术和神经阻滞等技术在管理癌症疼痛方面有效。然而,BC疼痛管理中的CAM疗法需要有足够的科学证据、决策以及监管机构的医学判断作为指导。BC疼痛管理基于仔细的常规疼痛评估以及对患者身体和心理的适当评估。疼痛控制是改善BC患者QoL的方法之一。如今患者可以获得药物和非药物疗法,但应谨慎使用,以尽量减少毒性并提高疗效。任何疼痛管理干预措施的使用都应基于适当的科学证据和集体医学判断。