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回顾心力衰竭合并阻塞性睡眠呼吸暂停时心房颤动关联的病理生理机制。

Pathophysiological Mechanisms to Review Association of Atrial Fibrillation in Heart Failure With Obstructive Sleep Apnea.

作者信息

Bandi Pushyami Satya, Panigrahy Preetish Kumar, Hajeebu Sreehita, Ngembus Ngonack J, Heindl Stacey E

机构信息

Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Pharmacology, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

出版信息

Cureus. 2021 Jul 1;13(7):e16086. doi: 10.7759/cureus.16086. eCollection 2021 Jul.

Abstract

Sleep-disordered breathing (SDB) comprising obstructive sleep apnea (OSA) is found in more than half of patients with heart failure (HF) and may have negative impacts on cardiovascular function. Increased atherosclerotic cardiovascular disease and the development of coronary events and congestive heart failure are associated with OSA. It is associated with a substandard quality of life, increased hospitalizations, and a poor prognosis. Despite its association with severe cardiovascular morbidity and mortality, the condition is frequently underdiagnosed. The substantial clinical evidence has established OSA as an independent risk factor for bradyarrhythmias and tachyarrhythmias in the last decade. The mechanisms which lead to such arrhythmias are uncertain. In short, OSA patients have a significantly elevated risk of HF and atrial fibrillation (AF). The direct correlation between HF, SDB, and cardiac arrhythmias has been poorly understood. The purpose of this study is to get a better understanding of the relation between AF, OSA, and HF by focusing on the pathophysiological mechanisms underlying these conditions. Therefore, we searched for articles to support our association in PubMed and Google Scholar databases.

摘要

在超过半数的心力衰竭(HF)患者中发现了包括阻塞性睡眠呼吸暂停(OSA)在内的睡眠呼吸紊乱(SDB),其可能对心血管功能产生负面影响。动脉粥样硬化性心血管疾病的增加以及冠状动脉事件和充血性心力衰竭的发展与OSA相关。它与生活质量不合格、住院次数增加以及预后不良有关。尽管其与严重的心血管发病率和死亡率相关,但该病症常常未被充分诊断。在过去十年中,大量临床证据已将OSA确立为缓慢性心律失常和快速性心律失常的独立危险因素。导致此类心律失常的机制尚不确定。简而言之,OSA患者发生HF和心房颤动(AF)的风险显著升高。HF、SDB和心律失常之间的直接关联一直未得到充分理解。本研究的目的是通过关注这些病症背后的病理生理机制,更好地理解AF、OSA和HF之间的关系。因此,我们在PubMed和谷歌学术数据库中搜索文章以支持我们的关联。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/44e0/8325395/53dfe26266fc/cureus-0013-00000016086-i01.jpg

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本文引用的文献

1
Atrial Fibrillation: Epidemiology, Pathophysiology, and Clinical Outcomes.
Circ Res. 2017 Apr 28;120(9):1501-1517. doi: 10.1161/CIRCRESAHA.117.309732.
2
Sleep-disordered breathing in heart failure.
Eur J Heart Fail. 2016 Apr;18(4):353-61. doi: 10.1002/ejhf.492. Epub 2016 Feb 11.
3
Obstructive Sleep Apnoea and Atrial Fibrillation.
Arrhythm Electrophysiol Rev. 2015 May;4(1):14-8. doi: 10.15420/aer.2015.4.1.14. Epub 2015 Mar 15.
4
Obstructive sleep apnea and its effects on cardiovascular diseases: a narrative review.
Anatol J Cardiol. 2015 Nov;15(11):944-50. doi: 10.5152/AnatolJCardiol.2015.6607.
5
Cardiac arrhythmias and sleep-disordered breathing in patients with heart failure.
Int J Mol Sci. 2014 Oct 16;15(10):18693-705. doi: 10.3390/ijms151018693.
6
Obstructive sleep apnea and atrial arrhythmogenesis.
Curr Cardiol Rev. 2014 Nov;10(4):362-8. doi: 10.2174/1573403x1004140707125137.
7
[Cheyne-Stokes respiration in patients with chronic heart failure: only a diagnostic marker or also a cardiovascular risk factor?].
Dtsch Med Wochenschr. 2014 May;139(19):1009-14. doi: 10.1055/s-0034-1369809. Epub 2014 Apr 29.
8
Effect of renal denervation on neurohumoral activation triggering atrial fibrillation in obstructive sleep apnea.
Hypertension. 2013 Oct;62(4):767-74. doi: 10.1161/HYPERTENSIONAHA.113.01728. Epub 2013 Aug 19.
9
The Relationship between Obstructive Sleep Apnea and Atrial Fibrillation: A Complex Interplay.
Pulm Med. 2013;2013:621736. doi: 10.1155/2013/621736. Epub 2013 Feb 26.

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