Pool J B, Greenough A, Gleeson J G, Price J F
Department of Child Health, King's College Hospital, London.
Arch Dis Child. 1988 Mar;63(3):288-91. doi: 10.1136/adc.63.3.288.
Changes in functional residual capacity and peak flow rate were measured to assess bronchodilator response to terbutaline inhaled via a nebuhaler. In 10 children with asthma, aged 5-7 years, five breaths sufficient to operate the nebuhaler valve resulted in clinically important improvement in both the functional residual capacity and the peak flow rate. In 18 of 22 children, aged 2-5 years, who were too young to have their peak flow rate measured reliably, terbutaline administered via this modified nebuhaler technique was also associated with a clinically important change in functional residual capacity. The results suggest that effective bronchodilation using a nebuhaler can be achieved even in very young children.
测量功能残气量和峰值流速的变化，以评估通过雾化器吸入特布他林后的支气管扩张反应。在10名5至7岁的哮喘儿童中，五次足以操作雾化器阀门的呼吸导致功能残气量和峰值流速均有临床上重要的改善。在22名2至5岁因年龄太小而无法可靠测量峰值流速的儿童中，有18名儿童通过这种改良的雾化器技术给予特布他林后，功能残气量也发生了临床上重要的变化。结果表明，即使是非常年幼的儿童，使用雾化器也能实现有效的支气管扩张。
