Department of Ophthalmology, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand.
BMC Ophthalmol. 2021 Aug 28;21(1):310. doi: 10.1186/s12886-021-02077-0.
This study aimed to develop a Thai version of the Dry Eye-Related Quality-of-Life Score (DEQS-Th) questionnaire and evaluate its validity, reliability, and feasibility among Thai participants.
The DEQS-Th, a 15-item self-report measuring dry eye and its impact on quality of life (QOL) was developed based on the DEQS. The questionnaire was divided into two subscales: Bothersome Ocular Symptoms (six questions), and Impact on Daily Life (nine questions). It employed a 5-point Likert scale, addressing on both the frequency and the degree of symptoms. Backward and forward and cultural adaptation process translation methods were employed. Thirty healthy participants were enrolled to evaluate the feasibility of the DEQS-Th in terms of difficulty and convenience. Reliability was assessed using internal consistency determined by Cronbach's alpha, with values > 0.7 considered acceptable. Convergent validity was determined by the correlation between DEQS-Th and overall health status. Confirmatory factor analysis was conducted for its factor structure.
The participants' mean age was 38.6 ± 12.9 years, and 23 (76.7%) were females. The mean time to complete the questionnaire was 9.3 ± 2.7 min. The Cronbach's alpha of the ocular symptoms subscale, impact on QOL subscale, and summary score on frequency and degree were 0.80 and 0.70, 0.89 and 0.89, and 0.90 and 0.89, respectively. The overall health status significantly correlated with the summary score (r = 0.564, p = .001), subscale ocular symptoms (r = 0.594, p = .001), and impact on QOL scores (r = 0.626, p < .001) of the DEQS-Th, respectively. A one-factor model fitted the data the best for both the ocular symptoms subscale (CFI = 1.000, TLI = 1.000, RMSEA = 0.000) and the impact on QOL subscale (CFI = 0.998, TLI = 0.997, RMSEA = 0.053).
When tested among normal participants, the DEQS-Th is a valid and reliable measurement for dry eye symptoms and impact on QOL.
本研究旨在开发泰文版干眼相关生活质量评分(DEQS-Th)问卷,并评估其在泰国参与者中的有效性、可靠性和可行性。
DEQS-Th 是一种 15 项自我报告量表,用于测量干眼及其对生活质量(QOL)的影响。该问卷分为两个分量表:眼部不适症状(6 个问题)和日常生活影响(9 个问题)。它采用 5 点 Likert 量表,同时评估症状的频率和严重程度。采用反向和正向翻译以及文化适应过程翻译方法。招募了 30 名健康参与者,以评估 DEQS-Th 在难度和方便性方面的可行性。使用 Cronbach's alpha 评估内部一致性,认为>0.7 的值可接受。采用 DEQS-Th 与总体健康状况之间的相关性来评估聚合效度。进行验证性因子分析以确定其因子结构。
参与者的平均年龄为 38.6±12.9 岁,23 名(76.7%)为女性。完成问卷的平均时间为 9.3±2.7 分钟。眼部症状分量表、对 QOL 的影响分量表和频率和严重程度的综合评分的 Cronbach's alpha 分别为 0.80 和 0.70、0.89 和 0.89、0.90 和 0.89。总体健康状况与综合评分(r=0.564,p=0.001)、眼部症状分量表(r=0.594,p=0.001)和对 QOL 的影响评分(r=0.626,p<0.001)显著相关。对于眼部症状分量表(CFI=1.000,TLI=1.000,RMSEA=0.000)和对 QOL 的影响分量表(CFI=0.998,TLI=0.997,RMSEA=0.053),单因素模型最适合数据。
在正常参与者中进行测试时,DEQS-Th 是一种用于测量干眼症状和对 QOL 影响的有效且可靠的测量工具。