South London and Maudsley NHS Foundation Trust, London SE5 8AZ, UK.
South London and Maudsley NHS Foundation Trust, London SE5 8AZ, UK.
Schizophr Res. 2021 Nov;237:1-8. doi: 10.1016/j.schres.2021.08.018. Epub 2021 Aug 27.
For adults with psychosis, international guidelines recommend individual and family based cognitive behavioural therapy interventions. Recommendations are extended to children and adolescents, based on adult research. It is also recommended that psychological interventions are offered for childhood presentations of psychotic-like or Unusual Experiences (UE), in the absence of a formal diagnosis, when these are Distressing (UEDs). Cognitive models underpinning these interventions require testing in adolescent populations, to further refine therapies. We address this need, by testing for the first time, the application of the adult cognitive model of psychosis to adolescent UEDs.
We used baseline data from the Coping with Unusual ExperienceS (CUES+) randomised controlled trial for 122 clinically referred adolescents (12-18 years) with self-reported UEDs. Known psychological mechanisms of adult cognitive models of psychosis; negative life events, affect (anxiety and depression), reasoning (jumping to conclusions bias), and schemas were investigated using multiple linear regression models, alongside variables particularly associated with the development and severity of adolescent UEDs and UE type (dissociation, externalising/behavioural problems, managing emotions).
The psychological mechanisms of adult cognitive models of psychosis explained 89% of the total variance of adolescent UED severity, F (10, 106) = 99.34, p < .0005, r = 0.89, with schemas as the principal significant contributor. Variance explained 40 - 72% across each of the UE types (paranoia, hallucinations, delusions, paranormal thinking and grandiosity).
Findings suggest that the psychological components of adult cognitive models of psychosis, particularly schemas, are also implicated in adolescent UEDs.
对于有精神病的成年人,国际指南建议采用个体和家庭为基础的认知行为疗法干预。基于成人研究,该建议也扩展到了儿童和青少年。还建议在没有正式诊断的情况下,对儿童出现类似精神病或异常体验(UE)的情况提供心理干预,当这些情况令人痛苦(UEDs)时。这些干预措施的认知模型需要在青少年人群中进行测试,以进一步完善治疗方法。我们通过首次测试成人精神病认知模型在青少年 UEDs 中的应用来满足这一需求。
我们使用了有临床就诊的 122 名青少年(12-18 岁)自我报告的 UE 随机对照试验 Coping with Unusual ExperienceS(CUES+)的基线数据。采用多元线性回归模型,研究了成人精神病认知模型的已知心理机制;负性生活事件、情绪(焦虑和抑郁)、推理(仓促结论偏差)和图式,同时还研究了与青少年 UED 和 UE 类型(分离、外化/行为问题、情绪管理)的发展和严重程度特别相关的变量。
成人精神病认知模型的心理机制解释了青少年 UED 严重程度的 89%的总方差,F(10,106)= 99.34,p <.0005,r = 0.89,其中图式是主要的显著贡献者。每种 UE 类型(妄想、幻觉、错觉、超自然思维和夸大)的方差解释率为 40-72%。
研究结果表明,成人精神病认知模型的心理成分,特别是图式,也与青少年 UED 有关。