儿童丘疹脓疱性皮炎：一种与 SARS-CoV-2 感染相关的独特的 PLEVA 样疹。10 例临床、组织病理学和免疫组化研究。
Papulo-purpuric dermatitis of childhood: a distinct PLEVA-like eruption associated to SARS-CoV-2 infection. Clinical, histopathological and immunohistochemical study of 10 cases.
机构信息
Department of Pathophysiology and Transplantation, Dermatology Unit, Università degli Studi di Milano, Foundation IRCCS, Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
Department of Clinical Sciences and Community Health, Pediatric Dermatology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
出版信息
Pediatr Dermatol. 2021 Sep;38(5):1185-1190. doi: 10.1111/pde.14777. Epub 2021 Aug 31.
Abstract
We observed ten children with a papular eruption with purpuric features during the SARS-CoV-2 pandemic in Northern Italy (May-December 2020). Histological examination showed signs of SARS-CoV-2-related dermatosis. Evidence of nucleocapsid viral proteins using SARS-CoV-2 (2019-nCoV) nucleocapsid antibody revealed cuticular staining of the deep portion of the eccrine glands in all cases.
摘要
我们在意大利北部 SARS-CoV-2 大流行期间观察到 10 例具有紫癜特征的丘疹性发疹患儿（2020 年 5 月至 12 月）。组织学检查显示与 SARS-CoV-2 相关的皮肤病迹象。使用 SARS-CoV-2（2019-nCoV）核衣壳抗体检测核衣壳病毒蛋白的证据显示，所有病例的外分泌腺深部均有角质层染色。
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