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纳米材料在抗菌应用中的新兴趋势。

Emerging Trends in Nanomaterials for Antibacterial Applications.

机构信息

International Ph.D. Program in Biomedical Engineering, College of Biomedical Engineering, Taipei Medical University, Taipei, 11031, Taiwan.

Institut de Recherche en Sciences de la Santé (IRSS-DRCO)/Nanoro, Ouagadougou, Burkina Faso.

出版信息

Int J Nanomedicine. 2021 Aug 26;16:5831-5867. doi: 10.2147/IJN.S328767. eCollection 2021.

DOI:10.2147/IJN.S328767
PMID:34475754
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8405884/
Abstract

Around the globe, surges of bacterial diseases are causing serious health threats and related concerns. Recently, the metal ion release and photodynamic and photothermal effects of nanomaterials were demonstrated to have substantial efficiency in eliminating resistance and surges of bacteria. Nanomaterials with characteristics such as surface plasmonic resonance, photocatalysis, structural complexities, and optical features have been utilized to control metal ion release, generate reactive oxygen species, and produce heat for antibacterial applications. The superior characteristics of nanomaterials present an opportunity to explore and enhance their antibacterial activities leading to clinical applications. In this review, we comprehensively list three different antibacterial mechanisms of metal ion release, photodynamic therapy, and photothermal therapy based on nanomaterials. These three different antibacterial mechanisms are divided into their respective subgroups in accordance with recent achievements, showcasing prospective challenges and opportunities in clinical, environmental, and related fields.

摘要

在全球范围内，细菌疾病的爆发正在造成严重的健康威胁和相关问题。最近，纳米材料的金属离子释放以及光动力和光热效应被证明在消除耐药性和细菌爆发方面具有很高的效率。具有表面等离子体共振、光催化、结构复杂性和光学特性等特性的纳米材料已被用于控制金属离子释放、生成活性氧物种以及产生热量以实现抗菌应用。纳米材料的卓越特性为探索和增强其抗菌活性以实现临床应用提供了机会。在这篇综述中，我们全面列出了基于纳米材料的金属离子释放、光动力疗法和光热疗法的三种不同抗菌机制。这三种不同的抗菌机制根据最近的研究成果分为各自的亚组，展示了临床、环境和相关领域的潜在挑战和机遇。

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