A review of features and characteristics of smart medication adherence products.

BACKGROUND

Smart medication adherence products (smart MAPs) capture and transmit real-time medication intake by using various means of connectivity, allowing for remote monitoring. Numerous such products with different features are available to address medication nonadherence. A comparison of the features of these products is needed for clinical decision-making. Therefore, the objective of this review was to compare smart MAPs available for in-home use.

METHODS

We searched grey and published literature and videos to identify smart MAPs. To be considered smart, products required 2 features: connectivity (the ability for collected data to exist outside the physical device) and automaticity (the ability for data to be analyzed or processed automatically). Products were excluded if product descriptions were not available in English, not for in-home use and unable to dispense medications.

RESULTS

Of the 51 products identified, 38 commercially available and 13 prototypes met the definition. Of these, 75% ( = 38) contained alarms, 24% ( = 12) were unit-dose, 63% ( = 32) were multidose, 43% ( = 22) had locking features, 41% ( = 21) were portable and 88% ( = 45) sent notifications to patients. The cost of marketed products, excluding subscriptions, ranged from $10 to $1500 USD. Some products required a monthly ( = 16) or yearly ( = 1) subscription ranging from $10 to $100 USD.

DISCUSSION

There is a growing market of smart MAPs for in-home patient use with variable features. Clinicians can use these features to identify and recommend products according to the specific needs of their patients to address medication adherence. 2021;154:xx-xx.