Department of Agrobiotechnology, Institute of Agriculture, RUDN University, 117198 Moscow, Russia.
Molecules. 2021 Sep 5;26(17):5402. doi: 10.3390/molecules26175402.
There is increased attention paid to metallic nanoparticles due to their intensive use in various branches of agriculture and biotechnology, such as pest management, nanosensors, gene delivery, seed treatment, etc. There has been growing interest in applying environmentally friendly strategies for synthesizing nanoparticles without using substances which are hazardous to the environment. Biological practices for the synthesis of nanoparticles have been considered as possible ecofriendly alternatives to chemical synthesis. In the present study, we used biogenic silver and copper nanoparticles which were prepared by a previously reported green method. Moreover, the problem of chemical residues, which usually remain along with chemically synthesized nanoparticles and limit their application, was solved by developing such a green synthesis approach. To study the antibacterial activity of silver and copper nanoparticles, was used; for the evaluation of antifungal activity, the pathogenic fungi , and sp. were applied. To the best of our knowledge, this study represents the first time that the antifungal impact of a nanoparticle has been tested on and sp. Silver nanoparticles were found to be the more effective antimicrobial agent against all examined pathogens in comparison to copper nanoparticles. Data from such investigations provide valuable preliminary data on silver nanoparticle-based compounds or composites for use in the management of different pathogens.
由于金属纳米粒子在农业和生物技术的各个领域（如害虫管理、纳米传感器、基因传递、种子处理等）的广泛应用，人们越来越关注它们。人们越来越感兴趣的是应用环保策略来合成纳米粒子，而不使用对环境有害的物质。生物合成纳米粒子的方法被认为是化学合成的可行的环保替代方法。在本研究中，我们使用了生物合成的银和铜纳米粒子，这些纳米粒子是通过以前报道的绿色方法制备的。此外，通过开发这种绿色合成方法，解决了通常与化学合成纳米粒子一起残留并限制其应用的化学残留物问题。为了研究银和铜纳米粒子的抗菌活性，使用了 ；为了评估抗真菌活性，应用了病原真菌 、 和 。据我们所知，这项研究首次测试了纳米粒子对 和 的抗真菌作用。与铜纳米粒子相比，银纳米粒子对所有被检测到的病原体都表现出更有效的抗菌作用。这些研究的数据为基于银纳米粒子的化合物或复合材料在管理不同病原体方面的应用提供了有价值的初步数据。
