Tang Pan, Cui Enhui, Song Yihong, Yan Ruoqian, Wang Jingyu
College of Veterinary Medicine, Northwest A&F University, Yangling, China.
Henan Centre for Animal Diseases Control and Prevention, Zhengzhou, China.
Arch Virol. 2021 Nov;166(11):2975-2988. doi: 10.1007/s00705-021-05226-4. Epub 2021 Sep 15.
Porcine deltacoronavirus (PDCoV) is one of the most important enteropathogenic pathogens, and it causes enormous economic losses to the global commercial pork industry. PDCoV was initially reported in Hong Kong (China) in 2012 and subsequently emerged in swine herds with diarrhea in Ohio (USA) in 2014. Since then, it has spread to Canada, South Korea, mainland China, and several Southeast Asian countries. Information about the epidemiology, evolution, prevention, and control of PDCoV and its prevalence in China has not been comprehensively reported, especially in the last five years. This review is an update of current information on the general characteristics, epidemiology, geographical distribution, and evolutionary relationships, and the status of PDCoV vaccine development, focusing on the prevalence of PDCoV in China and vaccine research in particular. Together, this information will provide us with a greater understanding of PDCoV infection and will be helpful for establishing new strategies for controlling this virus worldwide.
猪德尔塔冠状病毒（PDCoV）是最重要的肠道致病病原体之一，给全球商业猪肉产业造成巨大经济损失。PDCoV于2012年首次在中国香港被报道，随后于2014年在美国俄亥俄州出现腹泻症状的猪群中出现。从那时起，它已传播到加拿大、韩国、中国大陆和几个东南亚国家。关于PDCoV的流行病学、进化、预防和控制及其在中国的流行情况的信息尚未得到全面报道，尤其是在过去五年中。本综述是对有关PDCoV的一般特征、流行病学、地理分布和进化关系以及疫苗开发状况的最新信息的更新，重点关注PDCoV在中国的流行情况，特别是疫苗研究。这些信息将使我们对PDCoV感染有更深入的了解，并有助于制定全球控制这种病毒的新策略。
