Department of Oral Medicine, School of Dentistry, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
Social Determinants of Health Research Centre, Rafsanjan University of Medical Sciences, Rafsanjan, Iran.
BMC Oral Health. 2021 Sep 17;21(1):455. doi: 10.1186/s12903-021-01807-6.
The aim of this study was to investigate the association of denture stomatitis prevalence with cigarette, hookah and opium consumption and also dose-response relationship between the cigarette smoking duration and odds of denture stomatitis in population of Rafsanjan cohort center.
This cross-sectional study based on data of Rafsanjan Cohort Study (RCS) with 10,000 participants. After applying inclusion and exclusion criteria, 1619 participants were included in the analysis. Data were collected by oral examination and completion of pre-designed questionnaires to assess denture hygiene, smoking behavior, opium use and some other exposure variables. Multivariable logistic regression models were fitted to investigate possible association of cigarette, hookah and opium consumption and denture stomatitis.
Prevalence of denture stomatitis among all 1619 denture wearers was 21.6%. Cigarette smoking was associated with a higher odds of denture stomatitis, with the adjusted odds ratio (95% CI) of 2.29 (1.53-3.41). Also, dose-response increases were observed with the highest odds ratio in the 4th quartile for denture stomatitis (p-value < 0.001). Opium consumption was associated with a decreased odds of denture stomatitis (adjusted OR; 0.81, 95% CI 0.58-1.13) which was not statistically significant. Also interaction between opium consumption and cigarette smoking was not associated with higher odds of denture stomatitis (adjusted OR: 1.65, 95% CI 0.85-3.22).
Based on the findings of the present study, while cigarette smoking had a dose-response relationship with the increased odds of denture stomatitis; this association was not found with opium consumption.
本研究旨在探讨义齿性口炎的患病率与吸烟、水烟和鸦片消费的关系，以及吸烟时间与人群中义齿性口炎之间的剂量-反应关系。
这是一项基于 Rafsanjan 队列研究（RCS）数据的横断面研究，共有 10000 名参与者。在应用纳入和排除标准后，纳入了 1619 名参与者进行分析。通过口腔检查和填写预先设计的问卷收集数据，以评估义齿卫生、吸烟行为、鸦片使用和其他一些暴露变量。采用多变量逻辑回归模型来研究吸烟、水烟和鸦片消费与义齿性口炎的可能关联。
在所有 1619 名戴义齿的人中，义齿性口炎的患病率为 21.6%。吸烟与义齿性口炎的发生风险呈正相关，调整后的比值比（95%可信区间）为 2.29（1.53-3.41）。此外，还观察到剂量-反应增加，第 4 四分位数的比值比最高（p 值<0.001）。鸦片消费与义齿性口炎的发生风险呈负相关（调整后的比值比；0.81，95%可信区间 0.58-1.13），但无统计学意义。此外，鸦片消费与吸烟之间的交互作用与义齿性口炎的发生风险增加无关（调整后的比值比：1.65，95%可信区间 0.85-3.22）。
根据本研究的结果，虽然吸烟与义齿性口炎发生风险的增加呈剂量-反应关系，但与鸦片消费无关。
