Güneşliol Bartu Eren, Karaca Esen, Ağagündüz Duygu, Acar Zeynep Alanur
Department of Nutrition and Dietetics, Gazi University, Ankara, Turkey.
Department of Nutrition and Dietetics, Izmir Demokrasi University, Izmir, Turkey.
Crit Rev Food Sci Nutr. 2023;63(5):674-692. doi: 10.1080/10408398.2021.1952402. Epub 2021 Sep 23.
The aging of the population has great social and economic effects because it is characterized by a gradual loss in physiological integrity, resulting in functional decline, thereby loss of ability to move independently. Telomeres, the hallmarks of biological aging, play a protective role in both cell death and aging. Critically short telomeres give rise to a metabolically active cell that is unable to repair damage or divide, thereby leading to aging. Lifestyle factors such as physical activity (PA) and nutrition could be associated with telomere length (TL). Indeed, regular PA and healthy nutrition as integral parts of our lifestyle can slow down telomere shortening, thereby delaying aging. In this context, the present comprehensive review summarizes the data from recent literature on the association of PA and nutrition with TL.
人口老龄化具有重大的社会和经济影响，因为其特点是生理完整性逐渐丧失，导致功能衰退，进而丧失独立行动能力。端粒是生物衰老的标志，在细胞死亡和衰老过程中都发挥着保护作用。极短的端粒会产生一个代谢活跃但无法修复损伤或分裂的细胞，从而导致衰老。身体活动（PA）和营养等生活方式因素可能与端粒长度（TL）有关。事实上，规律的身体活动和健康的营养作为我们生活方式的组成部分，可以减缓端粒缩短，从而延缓衰老。在此背景下，本综述总结了近期文献中关于身体活动和营养与端粒长度关联的数据。
