Vargas-Mendoza Nancy, Angeles-Valencia Marcelo, Morales-González Ángel, Morales-Martínez Mauricio, Madrigal-Bujaidar Eduardo, Álvarez-González Isela, Fregoso-Aguilar Tomás, Delgado-Olivares Luis, Madrigal-Santillán Eduardo Osiris, Morales-González José A
Laboratorio de Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, Plan de San Luis y Díaz Mirón, Col. Casco de Santo Tomás, Del. Miguel Hidalgo, Ciudad de México 11340, Mexico.
Escuela Superior de Cómputo, Instituto Politécnico Nacional, Av. Juan de Dios Bátiz s/n Esquina Miguel Othón de Mendizabal, Unidad Profesional Adolfo López Mateos, Ciudad de México 07738, Mexico.
J Funct Morphol Kinesiol. 2021 Aug 30;6(3):72. doi: 10.3390/jfmk6030072.
Exercise training induces adaptive physiological and morphological modifications in the entire organism; however, excessive loads of training may increase damage in tissues. The purpose of this study was to evaluate the effect of silymarin in lung and liver histological changes in rats subjected to exercise training (ET).
Male Wistar rats were subjected to an 8-week ET treadmill program 5 days per week, 60 min/session, and were previously administered 100 mg ascorbic acid or 100 mg of silymarin.
Silymarin increased alveolar and bronchial muscle size, improve vascularization, and reduced tissue inflammation. In liver, silymarin promoted the reduction of lipid content.
Silymarin supplementation may improve inflammation in pulmonary tissue after 8 weeks of the ET treadmill program, improve cell recovery, and reduce intrahepatic lipid content.
运动训练可在整个机体中诱导适应性生理和形态学改变；然而，过度训练负荷可能增加组织损伤。本研究的目的是评估水飞蓟宾对接受运动训练（ET）大鼠肺和肝组织学变化的影响。
雄性Wistar大鼠每周5天、每次60分钟，进行为期8周的ET跑步机训练计划，且事先给予100mg抗坏血酸或100mg水飞蓟宾。
水飞蓟宾增加了肺泡和支气管肌肉大小，改善了血管生成，并减轻了组织炎症。在肝脏中，水飞蓟宾促进了脂质含量的降低。
补充水飞蓟宾可能改善ET跑步机训练计划8周后肺组织的炎症，促进细胞恢复，并降低肝内脂质含量。
