• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

实验室研究中银纳米颗粒和金纳米颗粒的当前知识——应用、毒性、细胞摄取

Current Knowledge of Silver and Gold Nanoparticles in Laboratory Research-Application, Toxicity, Cellular Uptake.

作者信息

Talarska Patrycja, Boruczkowski Maciej, Żurawski Jakub

机构信息

Department of Immunobiology, Poznan University of Medical Sciences, 60-806 Poznań, Poland.

出版信息

Nanomaterials (Basel). 2021 Sep 21;11(9):2454. doi: 10.3390/nano11092454.

DOI:10.3390/nano11092454
PMID:34578770
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8466515/
Abstract

Silver and gold nanoparticles can be found in a range of household products related to almost every area of life, including patches, bandages, paints, sportswear, personal care products, food storage equipment, cosmetics, disinfectants, etc. Their confirmed ability to enter the organism through respiratory and digestive systems, skin, and crossing the blood-brain barrier raises questions of their potential effect on cell function. Therefore, this manuscript aimed to summarize recent reports concerning the influence of variables such as size, shape, concentration, type of coating, or incubation time, on effects of gold and silver nanoparticles on cultured cell lines. Due to the increasingly common use of AgNP and AuNP in multiple branches of the industry, further studies on the effects of nanoparticles on different types of cells and the general natural environment are needed to enable their long-term use. However, some environmentally friendly solutions to chemically synthesized nanoparticles are also investigated, such as plant-based synthesis methods.

摘要

银纳米颗粒和金纳米颗粒存在于一系列与生活几乎各个领域相关的家用产品中,包括贴片、绷带、涂料、运动服装、个人护理产品、食品储存设备、化妆品、消毒剂等。它们经证实能够通过呼吸系统、消化系统、皮肤进入机体,并穿过血脑屏障,这引发了关于其对细胞功能潜在影响的问题。因此,本手稿旨在总结近期有关尺寸、形状、浓度、涂层类型或孵育时间等变量对金纳米颗粒和银纳米颗粒对培养细胞系影响的报告。由于银纳米颗粒和金纳米颗粒在多个行业分支中的使用日益普遍,需要进一步研究纳米颗粒对不同类型细胞和一般自然环境的影响,以便能够长期使用它们。然而,也在研究一些针对化学合成纳米颗粒的环保解决方案,例如基于植物的合成方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/e9e9f4e22140/nanomaterials-11-02454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/83184fb885ef/nanomaterials-11-02454-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/50d049279152/nanomaterials-11-02454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/e9e9f4e22140/nanomaterials-11-02454-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/83184fb885ef/nanomaterials-11-02454-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/50d049279152/nanomaterials-11-02454-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0b53/8466515/e9e9f4e22140/nanomaterials-11-02454-g003.jpg

相似文献

1
Current Knowledge of Silver and Gold Nanoparticles in Laboratory Research-Application, Toxicity, Cellular Uptake.实验室研究中银纳米颗粒和金纳米颗粒的当前知识——应用、毒性、细胞摄取
Nanomaterials (Basel). 2021 Sep 21;11(9):2454. doi: 10.3390/nano11092454.
2
Eco-friendly approach for nanoparticles synthesis and mechanism behind antibacterial activity of silver and anticancer activity of gold nanoparticles.环保型纳米粒子合成方法及银纳米粒子抗菌活性和金纳米粒子抗癌活性的作用机制。
Appl Microbiol Biotechnol. 2017 Jan;101(1):79-92. doi: 10.1007/s00253-016-8012-8. Epub 2016 Dec 3.
3
Plant-mediated green synthesis of metal-based nanoparticles for dermopharmaceutical and cosmetic applications.植物介导的基于金属的纳米粒子的绿色合成及其在皮肤病学和化妆品中的应用。
Int J Pharm. 2021 Mar 15;597:120311. doi: 10.1016/j.ijpharm.2021.120311. Epub 2021 Feb 1.
4
Properties of silver nanoparticles influencing their uptake in and toxicity to the earthworm Lumbricus rubellus following exposure in soil.影响纳米银颗粒在土壤中被蚯蚓(Lumbricus rubellus)摄取及其毒性的性质。
Environ Pollut. 2016 Nov;218:870-878. doi: 10.1016/j.envpol.2016.08.016. Epub 2016 Aug 11.
5
Antibacterial activity of biogenic silver and gold nanoparticles synthesized from Salvia africana-lutea and Sutherlandia frutescens.从非洲山黧豆和南非钩麻中生物合成的银和金纳米粒子的抗菌活性。
Nanotechnology. 2020 Dec 11;31(50):505607. doi: 10.1088/1361-6528/abb6a8.
6
Intracellular Transport of Silver and Gold Nanoparticles and Biological Responses: An Update.**标题**: 金纳米和银纳米颗粒的细胞内转运和生物学反应:最新进展 **摘要**: 本综述重点介绍了金纳米和银纳米颗粒的细胞内转运机制和相关的生物学效应。讨论了纳米颗粒的理化性质对其细胞内行为的影响,以及这些因素如何影响其在细胞内的分布、代谢和毒性。还讨论了纳米颗粒的细胞内转运与生物分子相互作用的关系,以及这些相互作用如何影响纳米颗粒的生物学效应。
Int J Mol Sci. 2018 Apr 27;19(5):1305. doi: 10.3390/ijms19051305.
7
Influence of gold, silver and gold-silver alloy nanoparticles on germ cell function and embryo development.金、银及金银合金纳米颗粒对生殖细胞功能和胚胎发育的影响。
Beilstein J Nanotechnol. 2015 Mar 5;6:651-664. doi: 10.3762/bjnano.6.66. eCollection 2015.
8
The Influence of Size and Chemical Composition of Silver and Gold Nanoparticles on in vivo Toxicity with Potential Applications to Central Nervous System Diseases.银和金纳米颗粒的尺寸和化学成分对体内毒性的影响及其在中枢神经系统疾病治疗中的潜在应用。
Int J Nanomedicine. 2021 Mar 15;16:2187-2201. doi: 10.2147/IJN.S260375. eCollection 2021.
9
Blood Biochemical and Hematological Study after Subacute Intravenous Injection of Gold and Silver Nanoparticles and Coadministered Gold and Silver Nanoparticles of Similar Sizes.亚急性静脉注射金和银纳米粒子及大小相似的金和银纳米粒子共给药后的血液生化和血液学研究。
Biomed Res Int. 2018 Jul 22;2018:8460910. doi: 10.1155/2018/8460910. eCollection 2018.
10
Interaction of silver nanoparticles with algae and fish cells: a side by side comparison.银纳米颗粒与藻类和鱼类细胞的相互作用:并列比较
J Nanobiotechnology. 2017 Feb 28;15(1):16. doi: 10.1186/s12951-017-0254-9.

引用本文的文献

1
In Situ Second Harmonic Generation and Extinction Spectroscopy for Studying Colloidal Gold-Silver-Gold Core-Shell-Shell Nanoparticle Growth Dynamics.用于研究胶体金-银-金核-壳-壳纳米颗粒生长动力学的原位二次谐波产生和消光光谱法
J Phys Chem C Nanomater Interfaces. 2025 Jun 13;129(26):12033-12042. doi: 10.1021/acs.jpcc.5c02596. eCollection 2025 Jul 3.
2
Advancing oral cancer care: nanomaterial-driven diagnostic and therapeutic innovations.推进口腔癌护理:纳米材料驱动的诊断与治疗创新
Cell Biol Toxicol. 2025 May 23;41(1):90. doi: 10.1007/s10565-025-10027-5.
3
Fighting RNA viruses with a gold nanoparticle Cas13d gene-editing armor.

本文引用的文献

1
Rutile nano-bio-interactions mediate dissimilar intracellular destiny in human skin cells.金红石纳米生物相互作用介导人类皮肤细胞中不同的细胞内命运。
Nanoscale Adv. 2019 Apr 12;1(6):2216-2228. doi: 10.1039/c9na00078j. eCollection 2019 Jun 11.
2
Silver Nanoparticles Stable to Oxidation and Silver Ion Release Show Size-Dependent Toxicity In Vivo.对氧化稳定且能释放银离子的银纳米颗粒在体内表现出尺寸依赖性毒性。
Nanomaterials (Basel). 2021 Jun 8;11(6):1516. doi: 10.3390/nano11061516.
3
PEGylated Gold Nanoparticles Grafted with N-Acetyl-L-Cysteine for Polymer Modification.
用金纳米颗粒Cas13d基因编辑“铠甲”对抗RNA病毒。
Mol Ther Nucleic Acids. 2025 Apr 17;36(2):102540. doi: 10.1016/j.omtn.2025.102540. eCollection 2025 Jun 10.
4
Innovative approaches to asthma treatment: harnessing nanoparticle technology.哮喘治疗的创新方法:利用纳米颗粒技术
Discov Nano. 2025 Feb 8;20(1):21. doi: 10.1186/s11671-025-04211-z.
5
Nanoparticles in gynecologic cancers: a bibliometric and visualization analysis.妇科癌症中的纳米颗粒:文献计量与可视化分析
Front Oncol. 2025 Jan 8;14:1465987. doi: 10.3389/fonc.2024.1465987. eCollection 2024.
6
Nanomedicine in the treatment of Alzheimer's disease: bypassing the blood-brain barrier with cutting-edge nanotechnology.纳米医学在阿尔茨海默病治疗中的应用:利用前沿纳米技术突破血脑屏障
Neurol Sci. 2025 Apr;46(4):1489-1507. doi: 10.1007/s10072-024-07871-4. Epub 2024 Dec 6.
7
Anti-inflammatory and anti-angiogenic effects of extract on liver toxicity induced by silver nanoparticles in vivo.对银纳米粒子诱导的肝毒性的体内抗炎和抗血管生成作用。
J Med Life. 2024 Jul;17(7):728-738. doi: 10.25122/jml-2024-0050.
8
Nanotechnology-driven therapies for neurodegenerative diseases: a comprehensive review.基于纳米技术的神经退行性疾病治疗方法:全面综述。
Ther Deliv. 2024;15(12):997-1024. doi: 10.1080/20415990.2024.2401307. Epub 2024 Sep 19.
9
Nanomaterials for Photothermal Antimicrobial Surfaces.用于光热抗菌表面的纳米材料。
ACS Omega. 2024 Jun 4;9(24):25575-25590. doi: 10.1021/acsomega.4c01449. eCollection 2024 Jun 18.
10
Himalayan lichen biomass for green synthesis of silver nanocolloids: growth kinetics, effect of pH and metal sensing.用于银纳米胶体绿色合成的喜马拉雅地衣生物量:生长动力学、pH值的影响及金属传感
R Soc Open Sci. 2024 Mar 6;11(3):231633. doi: 10.1098/rsos.231633. eCollection 2024 Mar.
接枝N-乙酰-L-半胱氨酸用于聚合物改性的聚乙二醇化金纳米颗粒
Nanomaterials (Basel). 2021 May 28;11(6):1434. doi: 10.3390/nano11061434.
4
Influence of Physicochemical Characteristics and Stability of Gold and Silver Nanoparticles on Biological Effects and Translocation across an Intestinal Barrier-A Case Study from In Vitro to In Silico.金和银纳米颗粒的物理化学特性及稳定性对生物效应和跨肠屏障转运的影响——一项从体外到计算机模拟的案例研究
Nanomaterials (Basel). 2021 May 21;11(6):1358. doi: 10.3390/nano11061358.
5
The Influence of Size and Chemical Composition of Silver and Gold Nanoparticles on in vivo Toxicity with Potential Applications to Central Nervous System Diseases.银和金纳米颗粒的尺寸和化学成分对体内毒性的影响及其在中枢神经系统疾病治疗中的潜在应用。
Int J Nanomedicine. 2021 Mar 15;16:2187-2201. doi: 10.2147/IJN.S260375. eCollection 2021.
6
Silver nanoparticles as a potential treatment against SARS-CoV-2: A review.银纳米粒子作为治疗 SARS-CoV-2 的潜在方法:综述。
Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2021 Sep;13(5):e1707. doi: 10.1002/wnan.1707. Epub 2021 Feb 27.
7
Biogenesis of silver nanoparticles to treat cancer, diabetes, and microbial infections: a mechanistic overview.银纳米粒子的生物发生及其在癌症、糖尿病和微生物感染治疗中的应用:机制概述。
Appl Microbiol Biotechnol. 2021 Mar;105(6):2261-2275. doi: 10.1007/s00253-021-11171-8. Epub 2021 Feb 16.
8
Green Silver and Gold Nanoparticles: Biological Synthesis Approaches and Potentials for Biomedical Applications.绿色、银色和金色纳米颗粒:生物合成方法及在生物医学中的应用潜力。
Molecules. 2021 Feb 5;26(4):844. doi: 10.3390/molecules26040844.
9
Gold nanoparticles: synthesis, physiochemical properties and therapeutic applications in cancer.金纳米颗粒:合成、物理化学性质及在癌症治疗中的应用。
Drug Discov Today. 2021 May;26(5):1284-1292. doi: 10.1016/j.drudis.2021.01.030. Epub 2021 Feb 4.
10
Mixed-monolayer functionalized gold nanoparticles for cancer treatment: Atomistic molecular dynamics simulations study.用于癌症治疗的混合单层功能化金纳米粒子:原子分子动力学模拟研究。
Biosystems. 2021 Apr;202:104354. doi: 10.1016/j.biosystems.2021.104354. Epub 2021 Jan 11.