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维生素 B6 在健康与疾病中的作用

Vitamin B6 in Health and Disease.

机构信息

Department of Medical Biochemistry, Wroclaw Medical University, 50-368 Wroclaw, Poland.

Department of Surgical Education, Wroclaw Medical University, 50-668 Wroclaw, Poland.

出版信息

Nutrients. 2021 Sep 17;13(9):3229. doi: 10.3390/nu13093229.

DOI:10.3390/nu13093229
PMID:34579110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8467949/
Abstract

Vitamin B6 is a fascinating molecule involved in the vast majority of changes in the human body because it is a coenzyme involved in over 150 biochemical reactions. It is active in the metabolism of carbohydrates, lipids, amino acids, and nucleic acids, and participates in cellular signaling. It is an antioxidant and a compound with the ability to lower the advanced glycation end products (AGE) level. In this review, we briefly summarize its involvement in biochemical pathways and consider whether its deficiency may be associated with various diseases such as diabetes, heart disease, cancer, or the prognosis of COVID-19.

摘要

维生素 B6 是一种引人入胜的分子,它参与了人体绝大多数的变化,因为它是一种参与超过 150 种生化反应的辅酶。它在碳水化合物、脂肪、氨基酸和核酸的代谢中活跃,并参与细胞信号传递。它是一种抗氧化剂,也是一种具有降低晚期糖基化终产物(AGE)水平的化合物。在这篇综述中,我们简要总结了它在生化途径中的参与情况,并考虑了其缺乏是否可能与各种疾病(如糖尿病、心脏病、癌症或 COVID-19 的预后)有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/fba1dc97e65f/nutrients-13-03229-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/a726fc85d4c9/nutrients-13-03229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/28c063625df5/nutrients-13-03229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/1ad900175b7a/nutrients-13-03229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/fba1dc97e65f/nutrients-13-03229-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/a726fc85d4c9/nutrients-13-03229-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/28c063625df5/nutrients-13-03229-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/1ad900175b7a/nutrients-13-03229-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/83ac/8467949/fba1dc97e65f/nutrients-13-03229-g004.jpg

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Depression and Vegetarians: Association between Dietary Vitamin B6, B12 and Folate Intake and Global and Subcortical Brain Volumes.抑郁与素食者:膳食维生素 B6、B12 和叶酸摄入量与大脑皮质和皮质下体积的关系。
Nutrients. 2021 May 24;13(6):1790. doi: 10.3390/nu13061790.
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A Review of the Role of Micronutrients and Bioactive Compounds on Immune System Supporting to Fight against the COVID-19 Disease.
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Sci Rep. 2025 Aug 1;15(1):28138. doi: 10.1038/s41598-025-12537-y.
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