新型冠状病毒肺炎对肌肉骨骼系统的影响：临床医生指南
Effects of COVID-19 on the Musculoskeletal System: Clinician's Guide.
作者信息
Hasan Laith K, Deadwiler Brittney, Haratian Aryan, Bolia Ioanna K, Weber Alexander E, Petrigliano Frank A
机构信息
USC Epstein Family Center for Sports Medicine at Keck Medicine of USC, Los Angeles, CA, USA.
出版信息
Orthop Res Rev. 2021 Sep 21;13:141-150. doi: 10.2147/ORR.S321884. eCollection 2021.
The global pandemic caused by SARS-CoV-2, or COVID-19, continues to impact all facets of daily life. Clinical manifestations of COVID-19 commonly include musculoskeletal symptoms such as myalgias, arthralgias, and neuropathies/myopathies. The inflammatory response and its impact on the respiratory system have been the focus of most studies. However, the literature is more limited regarding the inflammatory response and its implications for other organ systems, specifically the musculoskeletal system. Previous studies have described how systemic inflammation may play a role in bone and joint pathology. Furthermore, it is important to understand the effects current therapeutics used in the treatment of COVID-19 may have on the musculoskeletal system. In this study, we will review the current understanding of the effect COVID-19 has on the musculoskeletal system, provide an overview of musculoskeletal symptoms of patients infected with the virus, and address key issues for clinicians to address during the care of COVID-19 patients.
由严重急性呼吸综合征冠状病毒2（SARS-CoV-2）引发的全球大流行，即2019冠状病毒病（COVID-19），持续影响着日常生活的方方面面。COVID-19的临床表现通常包括肌肉骨骼症状，如肌痛、关节痛以及神经病变/肌病。炎症反应及其对呼吸系统的影响一直是大多数研究的重点。然而，关于炎症反应及其对其他器官系统，特别是肌肉骨骼系统的影响，相关文献较为有限。先前的研究已经描述了全身炎症如何在骨骼和关节病理学中发挥作用。此外，了解目前用于治疗COVID-19的疗法可能对肌肉骨骼系统产生的影响也很重要。在本研究中，我们将回顾目前对COVID-19对肌肉骨骼系统影响的认识，概述感染该病毒患者的肌肉骨骼症状，并探讨临床医生在照顾COVID-19患者期间需要解决的关键问题。
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