National Infection Service, Public Health England, London, UK.
Scottish E. coli O157/STEC Reference Laboratory, Edinburgh, UK.
Epidemiol Infect. 2021 Aug 10;149:e178. doi: 10.1017/S0950268821001576.
In October 2019, public health surveillance systems in Scotland identified an increase in the number of reported infections of Shiga toxin-producing Escherichia coli (STEC) O26:H11 involving bloody diarrhoea. Ultimately, across the United Kingdom (UK) 32 cases of STEC O26:H11 stx1a were identified, with the median age of 27 years and 64% were male; six cases were hospitalised. Among food exposures there was an association with consuming pre-packed sandwiches purchased at outlets belonging to a national food chain franchise (food outlet A) [odds ratio (OR) = 183.89, P < 0.001]. The common ingredient identified as a component of the majority of the sandwiches sold at food outlet A was a mixed salad of Apollo and Iceberg lettuce and spinach leaves. Microbiological testing of food and environmental samples were negative for STEC O26:H11, although STEC O36:H19 was isolated from a mixed salad sample taken from premises owned by food outlet A. Contamination of fresh produce is often due to a transient event and detection of the aetiological agent in food that has a short-shelf life is challenging. Robust, statistically significant epidemiological analysis should be sufficient evidence to direct timely and targeted on-farm investigations. A shift in focus from testing the microbiological quality of the produce to investigating the processes and practices through the supply chain and sampling the farm environment is recommended.
2019 年 10 月,苏格兰公共卫生监测系统发现报告的产志贺毒素大肠杆菌(STEC)O26:H11 感染病例数增加,涉及血性腹泻。最终,在英国(UK)共发现 32 例 STEC O26:H11 stx1a,中位年龄为 27 岁,64%为男性;6 例住院。在食物暴露方面,与食用在全国连锁食品店(食品店 A)购买的预包装三明治有关(比值比(OR)=183.89,P<0.001)。在食品店 A 出售的大多数三明治中,共同的成分是一种由 Apollo 和冰山生菜以及菠菜叶混合的沙拉。对食物和环境样本的微生物检测均未发现 STEC O26:H11,但从食品店 A 所有的混合沙拉样本中分离出了 STEC O36:H19。新鲜农产品的污染通常是由于偶发事件引起的,而且在保质期短的食物中检测到病原体具有挑战性。强有力的、具有统计学意义的流行病学分析应该足以作为证据,及时、有针对性地对农场进行调查。建议从检测农产品的微生物质量转向调查供应链中的流程和做法,并对农场环境进行采样。