Petri H, Tronnier H
Infection. 1986;14 Suppl 3:S213-6. doi: 10.1007/BF01667847.
Thirty-four patients suffering from various skin infections caused by gram-positive and gram-negative pathogens were treated with enoxacin (400 to 800 mg/day) for 8 to 14 days. A marked abatement of clinical symptoms, accompanied by eradication of the causative pathogens was observed in all 34 patients. Enoxacin was well tolerated. The minimal erythema dose of UVA light was reduced by a mean of 45% in three of the twenty patients receiving the 800 mg daily dosage of enoxacin. No positive reactions could be provoked in a subsequently applied photopatch test, allergic reactions were not observed. These mild reactions seen in a small percentage of patients appear to indicate further specific tests to determine a possible photosensitization effect of enoxacin.
34例由革兰氏阳性和革兰氏阴性病原体引起的各种皮肤感染患者，接受依诺沙星治疗（400至800毫克/天），疗程8至14天。所有34例患者临床症状均显著减轻，同时致病病原体被根除。依诺沙星耐受性良好。在接受每日800毫克依诺沙星剂量的20例患者中，有3例患者的UVA光最小红斑量平均降低了45%。在随后进行的光斑贴试验中未引发阳性反应，未观察到过敏反应。在一小部分患者中出现的这些轻微反应似乎表明需要进一步进行特定检测，以确定依诺沙星可能的光敏作用。
