Yao Zeyang, Xie Wen, Zhang Jiawei, Dong Yuhao, Qiu Hailong, Yuan Haiyun, Jia Qianjun, Wang Tianchen, Shi Yiyi, Zhuang Jian, Que Lifeng, Xu Xiaowei, Huang Meiping
School of Medicine, South China University of Technology, Guangzhou, China.
Guangdong Provincial Key Laboratory of South China Structural Heart Disease, Guangdong Cardiovascular Institute, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Guangzhou, China.
Front Physiol. 2021 Sep 27;12:732711. doi: 10.3389/fphys.2021.732711. eCollection 2021.
Type-B Aortic Dissection (TBAD) is one of the most serious cardiovascular events characterized by a growing yearly incidence, and the severity of disease prognosis. Currently, computed tomography angiography (CTA) has been widely adopted for the diagnosis and prognosis of TBAD. Accurate segmentation of true lumen (TL), false lumen (FL), and false lumen thrombus (FLT) in CTA are crucial for the precise quantification of anatomical features. However, existing works only focus on only TL and FL without considering FLT. In this paper, we propose ImageTBAD, the first 3D computed tomography angiography (CTA) image dataset of TBAD with annotation of TL, FL, and FLT. The proposed dataset contains 100 TBAD CTA images, which is of decent size compared with existing medical imaging datasets. As FLT can appear almost anywhere along the aorta with irregular shapes, segmentation of FLT presents a wide class of segmentation problems where targets exist in a variety of positions with irregular shapes. We further propose a baseline method for automatic segmentation of TBAD. Results show that the baseline method can achieve comparable results with existing works on aorta and TL segmentation. However, the segmentation accuracy of FLT is only 52%, which leaves large room for improvement and also shows the challenge of our dataset. To facilitate further research on this challenging problem, our dataset and codes are released to the public (Dataset, 2020).
B型主动脉夹层(TBAD)是最严重的心血管事件之一,其年发病率呈上升趋势,疾病预后严重。目前,计算机断层血管造影(CTA)已被广泛应用于TBAD的诊断和预后评估。在CTA中准确分割真腔(TL)、假腔(FL)和假腔血栓(FLT)对于精确量化解剖特征至关重要。然而,现有工作仅关注TL和FL,而未考虑FLT。在本文中,我们提出了ImageTBAD,这是首个带有TL、FL和FLT标注的TBAD的三维计算机断层血管造影(CTA)图像数据集。所提出的数据集包含100张TBAD CTA图像,与现有的医学影像数据集相比,规模适中。由于FLT几乎可以出现在主动脉沿线的任何位置,形状不规则,FLT的分割呈现出一类广泛的分割问题,即目标存在于各种位置且形状不规则。我们进一步提出了一种用于TBAD自动分割的基线方法。结果表明,该基线方法在主动脉和TL分割方面可取得与现有工作相当的结果。然而,FLT的分割准确率仅为52%,仍有很大的改进空间,也显示了我们数据集的挑战性。为便于对这一具有挑战性的问题进行进一步研究,我们将数据集和代码公开发布(数据集,2020)。