Benthem de Grave Xandra, Saltzmann Janine, Laurain Julia, Rodriguez Maria A, Molist Francesc, Dänicke Sven, Santos Regiane R
Schothorst Feed Research, Lelystad, Netherlands.
Institute of Animal Nutrition, Friedrich-Loeffler-Institute (FLI), Federal Research Institute for Animal Health, Brunswick, Germany.
Front Vet Sci. 2021 Sep 30;8:704796. doi: 10.3389/fvets.2021.704796. eCollection 2021.
This study evaluated the effect of an algoclay-based mycotoxin decontaminant on the levels of ZEN, DON, and their derivatives in the colostrum, milk, and serum of sows, as well as in the serum of weaned piglets after maternal mycotoxin exposure during the last week of gestation and during lactation of sows (26 days). For this, sows ( = 5) were fed diets artificially contaminated with 100 (LoZEN) or 300 (HiZEN) ppb ZEN, with or without an algoclay-based mycotoxin decontaminant in the highly contaminated diet. All diets contained 250 ppb deoxynivalenol (DON). Dietary treatments did not affect the performance of the sows and piglets. Only α-ZEL was significantly increased in the colostrum of sows fed the HiZEN diet, and this increase was even higher in the colostrum of the sows fed the HiZEN diet supplemented with the test decontaminant. However, no differences in milk mycotoxin levels were observed at weaning. The highest levels of ZEN, α-ZEL, and β-ZEL were observed in the serum of sows fed the HiZEN diet. When the HiZEN diet was supplemented with the tested algoclay-based mycotoxin decontaminant the levels of ZEN and its metabolites were significantly decreased in the serum of sows. Although all sows were fed the same levels of DON, the serum level of de-epoxy-DON was increased only in the serum of piglets from the sows fed a diet with the non-supplemented HiZEN diet. In conclusion, the tested algoclay-based mycotoxin decontaminant can decrease the levels of ZEN and its metabolites in the serum of sows and the level of de-DON in the serum of piglets.
本研究评估了一种基于蒙脱石的霉菌毒素去污剂对妊娠最后一周和母猪哺乳期（26天）母体霉菌毒素暴露后，母猪初乳、乳汁和血清以及断奶仔猪血清中玉米赤霉烯酮（ZEN）、脱氧雪腐镰刀菌烯醇（DON）及其衍生物水平的影响。为此，选用5头母猪，分别饲喂人为污染了100 ppb（低ZEN组，LoZEN）或300 ppb（高ZEN组，HiZEN）ZEN的日粮，高污染日粮中添加或不添加基于蒙脱石的霉菌毒素去污剂。所有日粮均含有250 ppb脱氧雪腐镰刀菌烯醇（DON）。日粮处理对母猪和仔猪的生产性能没有影响。仅高ZEN组日粮喂养的母猪初乳中α - 玉米赤霉烯醇（α-ZEL）显著增加，在添加了试验去污剂的高ZEN组日粮喂养的母猪初乳中这种增加更为明显。然而，断奶时乳汁中霉菌毒素水平未观察到差异。高ZEN组日粮喂养的母猪血清中ZEN、α-ZEL和β-ZEL水平最高。当高ZEN组日粮添加试验性的基于蒙脱石的霉菌毒素去污剂时，母猪血清中ZEN及其代谢产物水平显著降低。尽管所有母猪饲喂相同水平的DON，但仅在饲喂未添加去污剂的高ZEN组日粮的母猪所产仔猪血清中，脱环氧-DON的血清水平有所增加。总之，试验性的基于蒙脱石的霉菌毒素去污剂可降低母猪血清中ZEN及其代谢产物水平以及仔猪血清中脱DON水平。
