Clinic of Medicine, Faculty of Veterinary Medicine, University of Thessaly, 43100 Karditsa, Greece.
Institute of Technology of Agricultural Products, Hellenic Agricultural Organization-Demeter (HAO-Demeter), 14123 Athens, Greece.
Toxins (Basel). 2023 Sep 19;15(9):580. doi: 10.3390/toxins15090580.
This in vivo study aimed to investigate the effects of a multi-component mycotoxin-detoxifying agent, containing clays (bentonite, sepiolite), phytogenic feed additives (curcumin, silymarin) and postbiotics (yeast cell wall, hydrolyzed yeast) on the antioxidant capacity, health and reproductive performance of pregnant and lactating sows challenged by mycotoxins. Eighty (80) primiparous sows (mean age 366 ± 3 days) per each of the two trial farms were divided into two groups in each farm: a) T1 (control group): 40 sows received the contaminated feed and b) T2 group (experimental group): 40 sows received the contaminated feed plus the mycotoxin-detoxifying agent, one month before farrowing until the end of the lactation period. Thiobarbituric acid reactive substances (TBARS), protein carbonyls (CARBS) and total antioxidant capacity (TAC) were evaluated as biomarkers of oxidative stress. Clinical and reproductive parameters were recorded. Our results indicate that the administration of a multi-component mycotoxin-detoxifying agent's administration in sow feed has beneficial effects on oxidative stress biomarkers and can improve sows' health and performance.
本体内研究旨在探究一种多组分霉菌毒素解毒剂(包含膨润土、海泡石、植物源饲料添加剂(姜黄素、水飞蓟素)和后生元(酵母细胞壁、水解酵母))对受霉菌毒素挑战的妊娠和哺乳母猪的抗氧化能力、健康和繁殖性能的影响。在每个试验农场中,将 80 头(平均年龄 366 ± 3 天)初产母猪分为两组:a)T1(对照组):40 头母猪接受污染饲料,b)T2 组(实验组):40 头母猪在分娩前一个月至哺乳期结束时接受污染饲料加霉菌毒素解毒剂。丙二醛(TBARS)、蛋白羰基(CARBS)和总抗氧化能力(TAC)作为氧化应激的生物标志物进行评估。记录临床和繁殖参数。我们的结果表明,在母猪饲料中添加多组分霉菌毒素解毒剂对氧化应激生物标志物有有益影响,并能改善母猪的健康和性能。