Dastjerdi Shahriar, Malikan Mohammad, Akgöz Bekir, Civalek Ömer, Wiczenbach Tomasz, Eremeyev Victor A
Division of Mechanics, Civil Engineering Department, Akdeniz University, Antalya, Turkey.
Department of Mechanics of Materials and Structures, Faculty of Civil and Environmental Engineering, Gdansk University of Technology, Gdansk, Poland.
Int J Eng Sci. 2022 Jan 1;170:103604. doi: 10.1016/j.ijengsci.2021.103604. Epub 2021 Oct 29.
The SARS-CoV-2 virus, which has emerged as a Covid-19 pandemic, has had the most significant impact on people's health, economy, and lifestyle around the world today. In the present study, the SARS-CoV-2 virus is mechanically simulated to obtain its deformation and natural frequencies. The virus under analysis is modeled on a viscoelastic spherical structure. The theory of shell structures in mechanics is used to derive the governing equations. Whereas the virus has nanometric size, using classical theories may give incorrect results. Consequently, the nonlocal elasticity theory is used to consider the effect of interatomic forces on the results. From the mechanical point of view, if a structure vibrates with a natural frequency specific to it, the resonance phenomenon will occur in that structure, leading to its destruction. Therefore, it is possible that the protein chains of SARS-CoV-2 would be destroyed by vibrating it at natural frequencies. Since the mechanical properties of SARS-CoV-2 are not clearly known due to the new emergence of this virus, deformation and natural frequencies are obtained in a specific interval. Researchers could also use this investigation as a pioneering study to find a non-vaccine treatment solution for the SARS-CoV-2 virus and various viruses, including HIV.
引发新冠疫情的严重急性呼吸综合征冠状病毒2（SARS-CoV-2）病毒，对当今世界各国人民的健康、经济和生活方式产生了最为重大的影响。在本研究中，对SARS-CoV-2病毒进行了力学模拟，以获取其变形和固有频率。所分析的病毒采用粘弹性球形结构建模。运用力学中的壳体结构理论推导控制方程。鉴于该病毒具有纳米级尺寸，使用经典理论可能会得出错误结果。因此，采用非局部弹性理论来考虑原子间力对结果的影响。从力学角度来看，如果一个结构以其特定的固有频率振动，该结构将发生共振现象，从而导致其破坏。所以，SARS-CoV-2的蛋白质链有可能因以固有频率振动而遭到破坏。由于这种病毒是新出现的，其力学特性尚不清楚，因此在特定区间内获取了变形和固有频率。研究人员还可将本研究作为一项开拓性研究，为SARS-CoV-2病毒以及包括艾滋病病毒在内的各种病毒寻找非疫苗治疗方案。
