Majid Sadaf, Lodhi Omair Ul Haq, Niazi Asfandyar Khan, Lodhi Somair Ul Haq, Siddiqui Maimoona
Department of Neurology, Shifa International Hospital, Islamabad, Pakistan.
Proc (Bayl Univ Med Cent). 2021 Jun 29;34(6):664-667. doi: 10.1080/08998280.2021.1938471. eCollection 2021.
In stroke patients, a high neutrophil-to-lymphocyte ratio (NLR) has been associated with poor functional outcome at 3 months, higher mortality, and a higher hemorrhagic transformation. We assessed the role of NLR in patients with acute ischemic stroke who received thrombolysis. The charts of 98 patients treated between 2015 and 2019 were retrospectively reviewed. The mean NLR was compared using an independent Student's test. At 3 months, a good functional outcome was seen in 31 patients (32%) and a poor functional outcome was seen in 67 patients (68%). Patients with NLR >2.39 had a poor functional outcome (odds ratio 2.7; 95% confidence interval 1.11-6.39; < 0.02). Our study revealed that patients who present with acute ischemic stroke and have an increased NLR at the time of administration of thrombolysis have a poor functional outcome at 3 months.
在中风患者中，高中性粒细胞与淋巴细胞比值（NLR）与3个月时功能预后不良、死亡率较高以及出血性转化风险较高相关。我们评估了NLR在接受溶栓治疗的急性缺血性中风患者中的作用。对2015年至2019年期间接受治疗的98例患者的病历进行了回顾性分析。使用独立样本t检验比较平均NLR。3个月时，31例患者（32%）功能预后良好，67例患者（68%）功能预后不良。NLR>2.39的患者功能预后不良（比值比2.7；95%置信区间1.11 - 6.39；P<0.02）。我们的研究表明，急性缺血性中风患者在溶栓治疗时NLR升高，其3个月时功能预后不良。
