• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

腰椎感染病因：一例报告。

Lumbar infection caused by : A case report.

作者信息

Tan Ying-Zheng, Yuan Ting, Tan Liang, Tian Yu-Qiu, Long Yun-Zhu

机构信息

Department of Infectious Diseases, Zhuzhou Central Hospital, Zhuzhou 412000, Hunan Province, China.

Department of Spinal Surgery, Zhuzhou Central Hospital, Zhuzhou 412000, Hunan Province, China.

出版信息

World J Clin Cases. 2021 Oct 16;9(29):8879-8887. doi: 10.12998/wjcc.v9.i29.8879.

DOI:10.12998/wjcc.v9.i29.8879
PMID:34734070
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8546838/
Abstract

BACKGROUND

(), a slow-growing, acid-resistant mycobacterial species, was first isolated from the sputum of a lung infection patient in South Korea in 2014. Infections caused by are rare.

CASE SUMMARY

Herein, we report the case of a 53-year-old patient who presented with fever and low back pain. Lumbar nuclear magnetic resonance imaging revealed the destruction of the lumbar vertebra with peripheral abscess formation. After anti-infective and diagnostic anti-tuberculosis treatment, the patient had no further fever, but the back pain was not relieved. Postoperatively, the necrotic material was sent for pathological examination, and all tests related to tuberculosis were negative, but pus culture suggested nontuberculous mycobacteria. The necrotic tissue specimens were subjected to metagenomic next-generation sequencing, which indicated the presence of . Finally, the infecting pathogen was identified, and the treatment plan was adjusted. The patient was in good condition during the follow-up period.

CONCLUSION

, a rare nontuberculous mycobacterium, can also cause spinal infections. In the clinic, it is necessary to identify nontuberculous mycobacteria for spinal infections similar to .

摘要

背景

（）是一种生长缓慢、耐酸的分枝杆菌，于2014年首次从韩国一名肺部感染患者的痰液中分离出来。由（）引起的感染很罕见。

病例摘要

在此，我们报告一例53岁患者，其表现为发热和腰痛。腰椎核磁共振成像显示腰椎椎体破坏并伴有周围脓肿形成。经过抗感染和诊断性抗结核治疗后，患者不再发热，但腰痛未缓解。术后，将坏死物质送去做病理检查，所有与结核相关的检查均为阴性，但脓液培养提示非结核分枝杆菌。对坏死组织标本进行宏基因组二代测序，结果显示存在（）。最终，确定了感染病原体并调整了治疗方案。随访期间患者状况良好。

结论

（）是一种罕见的非结核分枝杆菌，也可引起脊柱感染。在临床上，对于类似（）引起的脊柱感染，有必要鉴定非结核分枝杆菌。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/83091f9a854d/WJCC-9-8879-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/d3deb6bb2447/WJCC-9-8879-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/978f03496dca/WJCC-9-8879-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/8fcdd3ca4934/WJCC-9-8879-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/ba6237254e7e/WJCC-9-8879-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/83091f9a854d/WJCC-9-8879-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/d3deb6bb2447/WJCC-9-8879-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/978f03496dca/WJCC-9-8879-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/8fcdd3ca4934/WJCC-9-8879-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/ba6237254e7e/WJCC-9-8879-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b369/8546838/83091f9a854d/WJCC-9-8879-g005.jpg

相似文献

1
Lumbar infection caused by : A case report.腰椎感染病因：一例报告。
World J Clin Cases. 2021 Oct 16;9(29):8879-8887. doi: 10.12998/wjcc.v9.i29.8879.
2
Evaluation of Q Gene Mycobacteria: A novel and easy nucleic acid chromatography method for mycobacterial species identification.评价 Q 基因分枝杆菌：一种新型且易于操作的分枝杆菌菌种鉴定核酸层析方法。
J Microbiol Methods. 2019 Aug;163:105657. doi: 10.1016/j.mimet.2019.105657. Epub 2019 Jun 19.
3
Lumbar Spine Infected by Mycobacterium tuberculosis and Cryptococcus neoformans: a Rare Case Report.腰椎结核分枝杆菌和新型隐球菌感染：一例罕见病例报告。
Clin Lab. 2024 Jun 1;70(6). doi: 10.7754/Clin.Lab.2024.240118.
4
A Two-Step Real-Time PCR Method To Identify Mycobacterium tuberculosis Infections and Six Dominant Nontuberculous Mycobacterial Infections from Clinical Specimens.一种两步实时 PCR 方法，用于从临床标本中鉴定结核分枝杆菌感染和六种主要的非结核分枝杆菌感染。
Microbiol Spectr. 2023 Aug 17;11(4):e0160623. doi: 10.1128/spectrum.01606-23. Epub 2023 Jun 28.
5
A Case of Pericarditis and Pericardial Masses Associated With Mycobacterium Paragordonae.1例与副戈登分枝杆菌相关的心包炎和心包肿物病例
Clin Med Insights Cardiol. 2023 Aug 24;17:11795468231189039. doi: 10.1177/11795468231189039. eCollection 2023.
6
is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes.是一种新兴的人类肺部疾病病原体：临床特征、抗菌药物敏感性检测和结果。
Emerg Microbes Infect. 2022 Dec;11(1):1973-1981. doi: 10.1080/22221751.2022.2103453.
7
Mixed infection of three nontuberculous mycobacteria species identified by metagenomic next-generation sequencing in a patient with peritoneal dialysis-associated peritonitis: a rare case report and literature review.宏基因组下一代测序鉴定腹膜透析相关性腹膜炎患者感染三种非结核分枝杆菌：一例罕见病例报告及文献复习。
BMC Nephrol. 2023 Apr 13;24(1):95. doi: 10.1186/s12882-023-03156-8.
8
Disseminated non-tuberculous mycobacterial infection caused by Mycobacterium obuense in an immunocompromised patient: a case report.免疫功能低下患者感染脓肿分枝杆菌导致播散性非结核分枝杆菌感染：病例报告。
BMC Infect Dis. 2023 Aug 8;23(1):517. doi: 10.1186/s12879-023-08510-7.
9
Disseminated nontuberculous mycobacterial infection with cryptic immunodeficiency mimicking malignancy: a case report.播散性非结核分枝杆菌感染伴隐匿性免疫缺陷，酷似恶性肿瘤：病例报告。
BMC Pulm Med. 2022 Nov 29;22(1):452. doi: 10.1186/s12890-022-02227-0.
10
A Rare Case of Mycobacterium Monacense Osteomyelitis: A Case Report.蒙纳森分枝杆菌骨髓炎1例罕见病例报告
Cureus. 2021 Mar 31;13(3):e14199. doi: 10.7759/cureus.14199.

引用本文的文献

1
A Case Report of Wound Infection Caused by .由……引起的伤口感染病例报告
Infect Drug Resist. 2025 Jun 27;18:3187-3197. doi: 10.2147/IDR.S513994. eCollection 2025.
2
Swollen Necrotic Lymphadenitis Infected with in an AIDS Patient: a Case Report and Literature Review.一名艾滋病患者感染的肿胀坏死性淋巴结炎：病例报告及文献综述
Infect Drug Resist. 2024 Aug 9;17:3475-3482. doi: 10.2147/IDR.S473762. eCollection 2024.
3
A Case of Pericarditis and Pericardial Masses Associated With Mycobacterium Paragordonae.1例与副戈登分枝杆菌相关的心包炎和心包肿物病例

本文引用的文献

1
Evaluation of Extraction Methods for Clinical Metagenomic Assay.临床宏基因组分析提取方法的评估
Microorganisms. 2020 Jul 27;8(8):1128. doi: 10.3390/microorganisms8081128.
2
Spinal Infections: An Update.脊柱感染：最新进展
Microorganisms. 2020 Mar 27;8(4):476. doi: 10.3390/microorganisms8040476.
3
Heat-killed Mycobacterium paragordonae therapy exerts an anti-cancer immune response via enhanced immune cell mediated oncolytic activity in xenograft mice model.灭活戈登分枝杆菌治疗通过增强免疫细胞介导的溶瘤活性在异种移植小鼠模型中发挥抗肿瘤免疫反应。
Clin Med Insights Cardiol. 2023 Aug 24;17:11795468231189039. doi: 10.1177/11795468231189039. eCollection 2023.
4
is an emerging pathogen in human pulmonary disease: clinical features, antimicrobial susceptibility testing and outcomes.是一种新兴的人类肺部疾病病原体：临床特征、抗菌药物敏感性检测和结果。
Emerg Microbes Infect. 2022 Dec;11(1):1973-1981. doi: 10.1080/22221751.2022.2103453.
Cancer Lett. 2020 Mar 1;472:142-150. doi: 10.1016/j.canlet.2019.12.028. Epub 2019 Dec 23.
4
Hot topics on vertebral osteomyelitis from the International Society of Antimicrobial Chemotherapy.国际抗微生物化疗协会关于脊椎骨髓炎的热点话题。
Int J Antimicrob Agents. 2019 Aug;54(2):125-133. doi: 10.1016/j.ijantimicag.2019.06.013. Epub 2019 Jun 13.
5
Clinical Metagenomic Next-Generation Sequencing for Pathogen Detection.临床宏基因组下一代测序在病原体检测中的应用。
Annu Rev Pathol. 2019 Jan 24;14:319-338. doi: 10.1146/annurev-pathmechdis-012418-012751. Epub 2018 Oct 24.
6
Prevalence, risk factors and prognosis of nontuberculous mycobacterial infection among people with bronchiectasis: a population survey.支气管扩张症患者非结核分枝杆菌感染的患病率、危险因素及预后：一项人群调查
Eur Respir J. 2018 May 10;51(5). doi: 10.1183/13993003.02469-2017. Print 2018 May.
7
Management of spinal infection: a review of the literature.脊柱感染的管理：文献综述
Acta Neurochir (Wien). 2018 Mar;160(3):487-496. doi: 10.1007/s00701-018-3467-2. Epub 2018 Jan 22.
8
A temperature sensitive Mycobacterium paragordonae induces enhanced protective immune responses against mycobacterial infections in the mouse model.一株温度敏感型戈登分枝杆菌可诱导增强小鼠对抗分枝杆菌感染的保护性免疫反应。
Sci Rep. 2017 Nov 9;7(1):15230. doi: 10.1038/s41598-017-15458-7.
9
Mycobacterium paragordonae: a rare cause of peritonitis in a peritoneal dialysis patient.副戈登分枝杆菌：腹膜透析患者腹膜炎的罕见病因。
Clin Nephrol. 2017 Dec;88(12):371-372. doi: 10.5414/CN109272.
10
Infections of the Spine.脊柱感染
Infect Dis Clin North Am. 2017 Jun;31(2):279-297. doi: 10.1016/j.idc.2017.01.003. Epub 2017 Mar 30.