Jacob Jyothi, Vijayakumar N, Olickal Jeby Jose
Govt. Ayurveda College, Trivandrum, Kerala, India.
Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
J Ayurveda Integr Med. 2021 Oct-Dec;12(4):695-699. doi: 10.1016/j.jaim.2021.06.015. Epub 2021 Nov 2.
Current medical intervention of Polycystic Ovarian Syndrome (PCOS) mainly includes hormonal therapies which have long-term health consequences.
This study aimed to evaluate the effect of natural drug satapushpa (Anethum sowa Kurz.) powder with tilatailam (sesame oil) as anupanam (vehicle) in oligomenorrhoea associated with PCOS.
A single-group, before and after intervention study in the outpatient department and inpatient department of Government Ayurveda teaching hospital for women and children was done among women aged 18-35 years. Individuals diagnosed with oligomenorrhoea for more than three consecutive menstrual cycles and fulfilling Rotterdam's criteria of PCOS were included. Six grams of powder was given morning and evening along with 12 ml of tilatailam for three months. Effectiveness was assessed at 3rd and 6th months.
A total of 30 patients were recruited; the mean (SD) age was 22.6 (3.9) years. Majority were students (86.7%), residing in urban areas (60%), and unmarried (80%). Almost one-third of the participants had kapha-vata prakriti. There was no significant change in menstrual duration and amount of bleeding. However, a significant reduction in the menstrual interval was observed after three months of treatment (p = <0.001). Similarly, the median interquartile range (IQR) volume of the right ovary was reduced from 10 (7.2-14.8) to 5.3 (4.7-7.6) cm (p=<0.001), and the median (IQR) volume of the left ovary reduced from 9.1 (6.7-11.9) to 5.1 (4.6-7.1) cm (p=<0.001).
Treating PCOS using satapushpa powder and tilatailam for three months effectively regularizes the menstrual interval and reduces ovarian volume.
多囊卵巢综合征（PCOS）目前的医学干预主要包括激素疗法，而这些疗法会产生长期健康影响。
本研究旨在评估以tilatailam（芝麻油）为载体的天然药物satapushpa（索瓦莳萝）粉对PCOS相关的月经过少的疗效。
在政府阿育吠陀妇女儿童医院的门诊部和住院部，对18至35岁的女性进行了一项单组干预前后研究。纳入连续三个以上月经周期诊断为月经过少且符合鹿特丹PCOS标准的个体。每天早晚服用6克粉末，并搭配12毫升tilatailam，持续三个月。在第3个月和第6个月评估疗效。
共招募了30名患者；平均（标准差）年龄为22.6（3.9）岁。大多数是学生（86.7%），居住在城市地区（60%），且未婚（80%）。近三分之一的参与者具有痰湿-风型体质。月经持续时间和出血量没有显著变化。然而，治疗三个月后月经周期显著缩短（p = <0.001）。同样，右卵巢的中位数四分位间距（IQR）体积从10（7.2 - 14.8）降至5.3（4.7 - 7.6）厘米（p = <0.001），左卵巢的中位数（IQR）体积从9.1（6.7 - 11.9）降至5.1（4.6 - 7.1）厘米（p = <0.001）。
使用satapushpa粉和tilatailam治疗PCOS三个月可有效使月经周期规律化并减小卵巢体积。
