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新泽西州白人男性的职业与肺癌风险

Occupation and lung cancer risk among New Jersey white males.

作者信息

Schoenberg J B, Stemhagen A, Mason T J, Patterson J, Bill J, Altman R

出版信息

J Natl Cancer Inst. 1987 Jul;79(1):13-21.

PMID:3474440
Abstract

The association of occupation with lung cancer risk was examined in a case-control study conducted in six areas of New Jersey. The study included 763 white males with incident histologically confirmed primary cancer of the trachea, bronchus, and lung and 900 general population white male controls selected from driver's license and death certificate files. Altogether, 27 employment categories had a smoking-adjusted odds ratio (OR) of 1.3 or greater; five of these with significantly high OR contributed to an occupational population attributable risk of 13%. Masons and tilesetters; janitors and cleaners; printing workers; and trucking service, warehousing, and storage workers had significantly high risks overall and for longer durations of employment. Shipbuilding workers had significantly high risk overall and for short duration of employment. Although the excess risk for all shipbuilding workers was primarily among those with reported exposure to asbestos, the risk was also high among welders, burners, sheet metal workers, and boilermakers with no reported asbestos exposure.

摘要

在新泽西州六个地区开展的一项病例对照研究中,对职业与肺癌风险之间的关联进行了调查。该研究纳入了763名组织学确诊为原发性气管、支气管和肺癌的白人男性患者,以及从驾照和死亡证明档案中选取的900名白人男性作为一般人群对照。共有27种职业类别的吸烟调整优势比(OR)为1.3或更高;其中5种职业的OR显著偏高,导致职业人群归因风险为13%。泥瓦匠和瓷砖工、门卫和清洁工、印刷工人以及货运服务、仓储和存储工人总体风险显著偏高,且就业时间越长风险越高。造船工人总体风险显著偏高,但就业时间较短。尽管所有造船工人的额外风险主要集中在报告接触过石棉的人群中,但在未报告接触石棉的焊工、燃烧工、钣金工和锅炉工中风险也很高。

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