Department of Epidemiology and Health Statistics, Xiangya School of Public Health, Central South University, Changsha 410078, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2021 Nov 15;23(11):1141-1148. doi: 10.7499/j.issn.1008-8830.2107031.
To investigate the epidemic situation of hand-foot-mouth disease (HFMD) in Hunan Province, China, from 2008 to 2019, as well as its spatial autocorrelation characteristics and spatial-temporal clustering, and to provide a reference for the prevention and control of HFMD in Hunan Province.
Spatial autocorrelation and spatial-temporal clustering analyses were used to analyze the monitoring data of HFMD in Hunan Province from 2008 to 2019.
The epidemic situation of HFMD in Hunan Province from 2008 to 2019 showed obvious seasonal distribution, with a low incidence rate in January to March and a high incidence rate in April to July. As for population distribution, children aged 0-5 years had the highest number of HFMD cases and accounted for 95.89% (1 460 391/1 522 910) of all cases, with a mean annual incidence rate of 2 197.784/100 000, and scattered children had the highest number of cases and accounted for 82.59% (1 257 739/1 522 910) of all cases. The global spatial autocorrelation analysis showed that the onset of HFMD in Hunan Province showed a significant clustering distribution, and the local spatial autocorrelation analysis showed that the high clustering areas of HFMD were mainly the districts and counties of Changsha, Zhuzhou, and Yueyang cities. Time-space scanning showed that clustering time was mainly April to July; the cases were clustered in the northeast of Hunan Province from 2008 to 2010 and in the central part of Hunan Province from 2011 to 2019.
The high incidence rate of HFMD is observed in April to July in Hunan Province. Children under 5 years of age are at a high risk of this disease. Spatial-temporal clustering is observed for the epidemic of HFMD, mainly clustered in the northeastern and central areas of Hunan Province. It is suggested that the results may be used as guidance to determine the key areas for HFMD prevention and control in Hunan Province and optimize the allocation of health resources.
分析 2008-2019 年中国湖南省手足口病（HFMD）的流行特征及时空聚集性，为湖南省 HFMD 的防控提供参考依据。
采用空间自相关和时空聚类分析方法，对湖南省 2008-2019 年 HFMD 监测数据进行分析。
湖南省 2008-2019 年 HFMD 流行特征呈明显季节性分布，1-3 月发病率较低，4-7 月发病率较高；人群分布以 0-5 岁儿童发病数最多，占总病例数的 95.89%（1 460 391/1 522 910），年均发病率为 2 197.784/10 万，散居儿童发病数最多，占总病例数的 82.59%（1 257 739/1 522 910）；全局空间自相关分析显示湖南省 HFMD 发病呈显著聚集性分布，局部空间自相关分析显示 HFMD 高发聚集区主要为长沙市、株洲市和岳阳市的区县；时空扫描结果显示聚集时间主要为 4-7 月，2008-2010 年聚集区位于湖南省东北部，2011-2019 年聚集区位于湖南省中部。
湖南省 HFMD 高发期为 4-7 月，5 岁以下儿童为高发人群，HFMD 发病存在时空聚集性，主要聚集在湖南省东北部和中部地区。本研究结果可为湖南省 HFMD 防控的重点地区提供参考依据，优化卫生资源配置。
