Volen Center and Biology Department, Brandeis University, Waltham, Massachusetts 02454
J Neurosci. 2021 Dec 15;41(50):10213-10221. doi: 10.1523/JNEUROSCI.1261-21.2021. Epub 2021 Nov 9.
Years of basic neuroscience on the modulation of the small circuits found in the crustacean stomatogastric ganglion have led us to study the effects of temperature on the motor patterns produced by the stomatogastric ganglion. While the impetus for this work was the study of individual variability in the parameters determining intrinsic and synaptic conductances, we are confronting substantial fluctuations in the stability of the networks to extreme temperature; these may correlate with changes in ocean temperature. Interestingly, when studied under control conditions, these wild-caught animals appear to be unchanged, but it is only when challenged by extreme temperatures that we reveal the consequences of warming oceans.
多年来,对甲壳类动物口胃神经节中小电路的调制的基础神经科学研究,使我们能够研究温度对由口胃神经节产生的运动模式的影响。虽然这项工作的动力是研究决定内在和突触电导率的参数的个体可变性,但我们正面临着网络对极端温度稳定性的大幅波动;这些波动可能与海洋温度的变化有关。有趣的是,当在对照条件下进行研究时,这些野生捕获的动物似乎没有变化,但只有在受到极端温度的挑战时,我们才会揭示海洋变暖的后果。