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Estimating the extent of asymptomatic COVID-19 and its potential for community transmission: Systematic review and meta-analysis.评估无症状新冠病毒感染的程度及其社区传播潜力:系统评价与荟萃分析。
J Assoc Med Microbiol Infect Dis Can. 2020 Dec 31;5(4):223-234. doi: 10.3138/jammi-2020-0030. eCollection 2020 Dec.
2
SARS-CoV-2 antibody prevalence in England following the first peak of the pandemic.英格兰在大流行首次高峰后 SARS-CoV-2 抗体流行率。
Nat Commun. 2021 Feb 10;12(1):905. doi: 10.1038/s41467-021-21237-w.
3
Incidence and risk factors of COVID-19-like symptoms in the French general population during the lockdown period: a multi-cohort study.封锁期间法国普通人群中出现 COVID-19 样症状的发生率和危险因素:一项多队列研究。
BMC Infect Dis. 2021 Feb 10;21(1):169. doi: 10.1186/s12879-021-05864-8.
4
Socioeconomic Disparities in Community Mobility Reduction and COVID-19 Growth.社会经济差异对社区流动性降低和 COVID-19 传播的影响。
Mayo Clin Proc. 2021 Jan;96(1):78-85. doi: 10.1016/j.mayocp.2020.10.019. Epub 2020 Oct 22.
5
Changing Disparities in Coronavirus Disease 2019 (COVID-19) Burden in the Ethnically Homogeneous Population of Hong Kong Through Pandemic Waves: An Observational Study.通过疫情波改变香港种族同质性人群中 2019 年冠状病毒病(COVID-19)负担的差异:一项观察性研究。
Clin Infect Dis. 2021 Dec 16;73(12):2298-2305. doi: 10.1093/cid/ciab002.
6
Nationwide seroprevalence of SARS-CoV-2 and identification of risk factors in the general population of the Netherlands during the first epidemic wave.荷兰第一波疫情期间全国范围内严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的血清流行率及普通人群风险因素的识别
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Ethnicity and clinical outcomes in COVID-19: A systematic review and meta-analysis.COVID-19中的种族与临床结局:一项系统评价与荟萃分析。
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Telework Before Illness Onset Among Symptomatic Adults Aged ≥18 Years With and Without COVID-19 in 11 Outpatient Health Care Facilities - United States, July 2020.11 家门诊医疗机构中≥18 岁有症状的 COVID-19 或无 COVID-19 成人出现症状前的远程工作情况 - 美国,2020 年 7 月。
MMWR Morb Mortal Wkly Rep. 2020 Nov 6;69(44):1648-1653. doi: 10.15585/mmwr.mm6944a4.
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Neighbourhood income and physical distancing during the COVID-19 pandemic in the United States.美国 COVID-19 大流行期间的邻里收入与物理隔离。
Nat Hum Behav. 2020 Dec;4(12):1294-1302. doi: 10.1038/s41562-020-00998-2. Epub 2020 Nov 3.
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COVID-19 in New Zealand and the impact of the national response: a descriptive epidemiological study.新西兰的 COVID-19 疫情及国家应对措施的影响:一项描述性流行病学研究。
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社会不平等与新冠肺炎早期疫情动态:法国前瞻性队列研究。

Social inequalities and dynamics of the early COVID-19 epidemic: a prospective cohort study in France.

机构信息

Institut de Recherche Interdisciplinaire sur les enjeux Sociaux - Sciences sociales, politique, santé, IRIS (UMR 8156 CNRS - EHESS - U997 INSERM), Aubervilliers, France

INED, Paris, France.

出版信息

BMJ Open. 2021 Nov 11;11(11):e052888. doi: 10.1136/bmjopen-2021-052888.

DOI:10.1136/bmjopen-2021-052888
PMID:34764173
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8587531/
Abstract

OBJECTIVE

Although social inequalities in COVID-19 mortality by race, gender and socioeconomic status are well documented, less is known about social disparities in infection rates and their shift over time. We aim to study the evolution of social disparities in infection at the early stage of the epidemic in France with regard to the policies implemented.

DESIGN

Random population-based prospective cohort.

SETTING

From May to June 2020 in France.

PARTICIPANTS

Adults included in the Epidémiologie et Conditions de Vie cohort (n=77 588).

MAIN OUTCOME MEASURES

Self-reported anosmia and/or ageusia in three categories: no symptom, during the first epidemic peak (in March 2020) or thereafter (during lockdown).

RESULTS

In all, 2052 participants (1.53%) reported anosmia/ageusia. The social distribution of exposure factors (density of place of residence, overcrowded housing and working outside the home) was described. Multinomial regressions were used to identify changes in social variables (gender, class and race) associated with symptoms of anosmia/ageusia. Women were more likely to report symptoms during the peak and after. Racialised minorities accumulated more exposure risk factors than the mainstream population and were at higher risk of anosmia/ageusia during the peak and after. By contrast, senior executive professionals were the least exposed to the virus with the lower rate of working outside the home during lockdown. They were more affected than lower social classes at the peak of the epidemic, but this effect disappeared after the peak.

CONCLUSION

The shift in the social profile of the epidemic was related to a shift in exposure factors under the implementation of a stringent stay-at-home order. Our study shows the importance to consider in a dynamic way the gender, socioeconomic and race direct and indirect effects of the COVID-19 pandemic, notably to implement policies that do not widen health inequalities.

摘要

目的

尽管种族、性别和社会经济地位方面的 COVID-19 死亡率存在社会不平等现象已得到充分记录,但人们对感染率的社会差异及其随时间的变化知之甚少。我们旨在研究与所实施政策相关的法国疫情早期感染的社会差异演变。

设计

随机人群前瞻性队列研究。

地点

2020 年 5 月至 6 月期间在法国。

参与者

纳入 Epidémiologie et Conditions de Vie 队列的成年人(n=77588)。

主要观察指标

分为无症状、2020 年 3 月疫情高峰期(第一波)期间和之后(封锁期间)三种情况报告的嗅觉丧失和/或味觉丧失。

结果

共有 2052 名参与者(1.53%)报告嗅觉丧失/味觉丧失。描述了接触因素(居住密度、过度拥挤的住房和在家外工作)的社会分布。使用多项回归分析确定与嗅觉丧失/味觉丧失相关的社会变量(性别、阶层和种族)的变化。女性在高峰期和之后更有可能报告症状。种族化少数群体比主流人群积累了更多的暴露危险因素,在高峰期和之后更有可能出现嗅觉丧失/味觉丧失。相比之下,高级管理人员在封锁期间在家外工作的比例最低,接触病毒的风险最低。在疫情高峰期,他们比社会较低阶层受影响更大,但这种影响在高峰期后消失。

结论

在实施严格的居家令的情况下,接触因素的变化导致了疫情社会特征的转变。我们的研究表明,重要的是要以动态的方式考虑 COVID-19 大流行的性别、社会经济和种族的直接和间接影响,特别是要实施不会扩大健康不平等的政策。