Department of Plastic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People's Republic of China.
Int J Nanomedicine. 2021 Nov 3;16:7391-7416. doi: 10.2147/IJN.S331639. eCollection 2021.
Liposomes are ubiquitous tools in biomedical applications, such as drug delivery, membrane science and artificial cell. Micro- and nanofabrication techniques have revolutionized the preparation of liposomes on the microscale. State-of-the-art liposomal formation on microfluidic chips and its associated applications are introduced in this review. We attempt to provide a reference for liposomal researchers by comparing various microfluidic techniques for liposomes formation.
脂质体是生物医学应用中无处不在的工具,例如药物输送、膜科学和人工细胞。微纳加工技术已经彻底改变了微尺度上脂质体的制备。本文综述了微流控芯片上的最新脂质体形成及其相关应用。我们通过比较各种用于脂质体形成的微流控技术,试图为脂质体研究人员提供参考。