Rehabilitation Hospital of the Pacific, Honolulu, HI (CT, EL).
University of Hawai'i Cancer Center, Honolulu, HI (EOB).
Hawaii J Health Soc Welf. 2021 Nov;80(11):263-269.
Cancer diagnosis and treatment often negatively impact quality of life, worsening prognosis, and long-term survival in cancer patients. Rehabilitation is effective at reversing cancer-related effects, but these services are not standardized. An implementation study was conducted to determine the usability and efficacy of group-based exercise therapy delivered from an outpatient therapy clinic. Thirty breast cancer patients (mean age ± standard deviation [SD],= 55 ± 10 years) completed 36 90-minute group-based exercise sessions in small groups. Team-based exercises were used to foster peer interaction and social support. Usability was evaluated with participant feedback, adherence, and occurrence of adverse events. Effectiveness was measured with the Revised Piper Fatigue, the City of Hope Quality of Life (QOL), and the Beck Depression Inventories. Paired t-tests and 2-way ANOVAs were used to detect significance (P<.05); Cohen's d was used to measure effect size. Twenty-five patients completed the program; they reported that they liked the program design. One anticipated, moderate adverse event occurred. The intervention improved fatigue and QOL, where significant main effects of time were detected [Fatigue: (F(1,76)=29.78, P <.001); QOL: (F(1,80)=24.42, P<.0001)]. Improvements in the fatigue inventory's behavioral/security and sensory dimensions (Cohen's d=-0.43 and ȡ0.68, respectively) and the physical dimension of the QOL inventory were detected (Cohen's d=0.92). There were no significant changes in depression (P=.0735). Seven patients continued to participate in exercise classes for 2.5-years post-intervention, demonstrating achievability of program maintenance. Providing group-based exercise therapy services at an outpatient clinic is an effective and practical approach to improve cancer patients' QOL.
癌症的诊断和治疗常常对患者的生活质量产生负面影响，使预后恶化，生存时间缩短。康复对于逆转癌症相关影响是有效的，但这些服务尚未标准化。本实施研究旨在确定从门诊治疗诊所提供的基于小组的运动疗法的可用性和疗效。30 名乳腺癌患者（平均年龄±标准差[SD]，= 55 ± 10 岁）完成了 36 次 90 分钟的小组基于运动的小组练习。团队运动用于促进同伴互动和社会支持。通过参与者的反馈、依从性和不良事件的发生来评估可用性。使用修订版 Piper 疲劳量表、希望之城生活质量量表（QOL）和贝克抑郁量表来衡量有效性。使用配对 t 检验和双向方差分析来检测显著性（P<.05）；使用 Cohen's d 来衡量效应大小。25 名患者完成了该计划；他们报告说他们喜欢该计划的设计。发生了一起预期的中度不良事件。干预措施改善了疲劳和生活质量，时间的主要影响具有统计学意义[疲劳：（F(1,76)=29.78，P <.001）；QOL：（F(1,80)=24.42，P<.0001）]。疲劳量表的行为/安全性和感觉维度（Cohen's d=-0.43 和 ȡ0.68，分别）和 QOL 量表的身体维度都有所改善（Cohen's d=0.92）。抑郁没有明显变化（P=.0735）。7 名患者在干预后 2.5 年继续参加运动课程，证明了该计划能够维持。在门诊诊所提供小组运动疗法服务是改善癌症患者生活质量的有效且实用的方法。
