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用于个性化新冠病毒诊断的小型无标记智能手机辅助电化学传感方法

Miniaturized label-free smartphone assisted electrochemical sensing approach for personalized COVID-19 diagnosis.

作者信息

Chandra Pranjal

机构信息

Laboratory of Bio-Physio Sensors and Nanobioengineering, School of Biochemical Engineering, Indian Institute of Technology (BHU) Varanasi, Varanasi, Uttar Pradesh, 221005, India.

出版信息

Sens Int. 2020;1:100019. doi: 10.1016/j.sintl.2020.100019. Epub 2020 Jul 24.

Abstract

The COVID-19, coronavirus disease is an infectious disease caused by a novel virus called Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). By March 2020 the novel coronavirus known to cause a pandemic has infected nearly about 119 thousand people and killed more than 4,300 around 114 countries. Apart from the current controversial opinions about the origin, spreading, and sociological impact, it is much more imperative to put a halt to this current situation. Understanding, testing, and early to rapid diagnosis may be now the only key that can contain COVID-19 by "flattening the curve". Biosensing is the platform that allows rapid, highly sensitive, and selective detection of analytes which in turn can serve the purpose for fast and precise detection of COVID-19. In this article, based on recently reported miniaturized sensing strategies, we hereby propose a promising personalized smartphone assisted electrochemical sensing platform for diagnosis of COVID-19.

摘要

新型冠状病毒肺炎(COVID-19)是一种由名为严重急性呼吸综合征冠状病毒2(SARS-CoV-2)的新型病毒引起的传染病。截至2020年3月,已知导致大流行的新型冠状病毒已在约114个国家感染了近11.9万人,并造成4300多人死亡。除了目前关于病毒起源、传播和社会影响的争议性观点外,更迫切的是要阻止当前这种情况。理解、检测以及早期到快速诊断现在可能是通过“拉平曲线”来控制COVID-19的唯一关键。生物传感是一种能够对分析物进行快速、高灵敏度和高选择性检测的平台,这反过来又可用于快速、精确地检测COVID-19。在本文中,基于最近报道的小型化传感策略,我们特此提出一种用于诊断COVID-19的、有前景的个性化智能手机辅助电化学传感平台。

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