Departamento de Química Analítica, Facultad de Ciencias Químicas, Universidad Complutense de Madrid, 28040 Madrid, España.
ACS Sens. 2023 Sep 22;8(9):3276-3293. doi: 10.1021/acssensors.3c01172. Epub 2023 Aug 3.
Electrochemical affinity biosensors are evolving at breakneck speed, strengthening and colonizing more and more niches and drawing unimaginable roadmaps that increasingly make them protagonists of our daily lives. They achieve this by combining their intrinsic attributes with those acquired by leveraging the significant advances that occurred in (nano)materials technology, bio(nano)materials and nature-inspired receptors, gene editing and amplification technologies, and signal detection and processing techniques. The aim of this Perspective is to provide, with the support of recent representative and illustrative literature, an updated and critical view of the repertoire of opportunities, innovations, and applications offered by electrochemical affinity biosensors fueled by the key alliances indicated. In addition, the imminent challenges that these biodevices must face and the new directions in which they are envisioned as key players are discussed.
电化学亲和生物传感器正在飞速发展，不断强化和开拓更多的领域，并绘制出令人难以想象的路线图，使它们越来越成为我们日常生活的主角。它们通过将自身固有属性与通过利用（纳米）材料技术、生物（纳米）材料和受自然启发的受体、基因编辑和扩增技术以及信号检测和处理技术所获得的属性相结合来实现这一目标。本观点的目的是在最近有代表性和说明性的文献的支持下，提供一个更新的、批判性的视角，探讨由关键联盟推动的电化学亲和生物传感器所提供的机会、创新和应用的范围。此外，还讨论了这些生物器件必须面对的紧迫挑战，以及它们作为关键参与者的新方向。
