Institution of Biophotonics, National Yang Ming Chiao Tung University, Taipei 112, Taiwan.
Department of Research, Shin Kong Wu Ho-Su Memorial Hospital, Taipei 111, Taiwan.
Sensors (Basel). 2021 Oct 29;21(21):7220. doi: 10.3390/s21217220.
Numerous studies indicated the physical benefits of regular exercise, but the neurophysiological mechanisms of regular exercise in elders were less investigated. We aimed to compare changes in brain activity during exercise in elderly people and in young adults with and without regular exercise habits. A total of 36 healthy young adults (M/F:18/18) and 35 healthy elderly adults (M/F:20/15) participated in this study. According to exercise habits, each age group were classified into regular and occasional exerciser groups. ECG, EEG, and EMG signals were recorded using V-AMP with a 1-kHz sampling rate. The participants were instructed to perform three 5-min bicycle rides with different exercise loads. The EEG spectral power of elders who exercised regularly revealed the strongest positive correlation with their exercise intensity by using Pearson correlation analysis. The results demonstrate that exercise-induced significant cortical activation in the elderly participants who exercised regularly, and most of the -values are less than 0.001. No significant correlation was observed between spectral power and exercise intensity in the elders who exercised occasionally. The young participants who exercised regularly had greater cardiac and neurobiological efficiency. Our results may provide a new exercise therapy reference for adult groups with different exercise habits, especially for the elders.
大量研究表明，定期运动对身体有益，但对老年人定期运动的神经生理学机制的研究较少。我们旨在比较有规律运动习惯的老年人、青年人和无规律运动习惯的老年人和青年人在运动时大脑活动的变化。共有 36 名健康的年轻人（男女：18/18）和 35 名健康的老年人（男女：20/15）参加了这项研究。根据运动习惯，每个年龄组分为有规律运动者组和偶尔运动者组。使用 V-AMP 以 1 kHz 的采样率记录心电图（ECG）、脑电图（EEG）和肌电图（EMG）信号。参与者被指示进行三次不同运动负荷的 5 分钟自行车骑行。通过使用 Pearson 相关分析，对有规律运动的老年人的脑电图频谱功率进行分析，发现其与运动强度呈最强正相关。结果表明，有规律运动的老年人参与者的运动诱导出显著的皮质激活，其中大部分 -值小于 0.001。偶尔运动的老年人中，频谱功率与运动强度之间没有观察到显著相关性。有规律运动的年轻参与者具有更大的心脏和神经生物学效率。我们的研究结果可能为具有不同运动习惯的成年人群体，特别是老年人，提供一种新的运动治疗参考。
