Department of Clinical Research, The First Affiliated Hospital of Jinan University, 613 West Huangpu Avenue, Tianhe District, Guangzhou, 510630, Guangdong, China.
School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, 710061, Shaanxi, China.
Sleep Breath. 2022 Dec;26(4):1593-1601. doi: 10.1007/s11325-021-02522-w. Epub 2021 Nov 15.
This research aimed at determining the relationship between self-reported sleep duration during week-/work-days and metabolic syndrome (MetS) from NHANES 2013 to 2016.
This study analyzed data from 11,181 people aged 16 or older who took part in the NHANES (National Health and Nutrition Examination Surveys) from 2013 to 2016. A standard questionnaire was used to define self-reported sleep duration, and MetS was defined on the basis of the NCEP (National Cholesterol Education Program)/ATP III revised diagnostic criteria. Logistic regression and restricted cubic splines (RCS) models were used to assess the relationship between self-reported sleep duration and MetS.
The overall prevalence of MetS in the study cohort was 26.1%, with 24.8% for males and 27.3% for females. After adjusting for potential confounding factors, MetS was significantly associated with self-reported short sleep duration (odds ratio = 1.16, 95% confidence interval = 1.03-1.31, P = 0.013) but not with long sleep duration (P = 0.117). RCS regression revealed that self-reported sleep duration was nonlinearly related to MetS (P for nonlinearity = 0.0026). The risk of MetS decreased with increased sleep duration for durations of less than 7 h/day, while there was no association for longer sleep durations.
These results suggest that self-reported short sleep duration is a risk factor for MetS, while long sleep duration is not.
本研究旨在确定 2013 年至 2016 年 NHANES 中自我报告的工作日/周睡眠时间与代谢综合征（MetS）之间的关系。
本研究分析了 2013 年至 2016 年参加 NHANES（国家健康和营养检查调查）的 11181 名 16 岁或以上人群的数据。使用标准问卷定义自我报告的睡眠时间，根据 NCEP（国家胆固醇教育计划）/ATP III 修订的诊断标准定义 MetS。使用逻辑回归和限制立方样条（RCS）模型评估自我报告的睡眠时间与 MetS 之间的关系。
研究队列中 MetS 的总体患病率为 26.1%，男性为 24.8%，女性为 27.3%。在调整潜在混杂因素后，MetS 与自我报告的短睡眠时间显著相关（比值比=1.16，95%置信区间=1.03-1.31，P=0.013），但与长睡眠时间无关（P=0.117）。RCS 回归显示，自我报告的睡眠时间与 MetS 呈非线性相关（非线性检验 P=0.0026）。睡眠时间少于 7 小时/天，随着睡眠时间的增加，MetS 的风险降低，而睡眠时间较长时则没有关联。
这些结果表明，自我报告的短睡眠时间是 MetS 的一个危险因素，而长睡眠时间则不是。
