Gaspar Rui, Castelo Branco Catarina, Macedo Guilherme
Department of Gastroenterology and Hepatology, Centro Hospitalar de São João, Porto 4200, Portugal.
Department of Internal Medicine, Centro Hospitalar e Universitário do Porto, Porto 4100, Portugal.
World J Hepatol. 2021 Oct 27;13(10):1367-1377. doi: 10.4254/wjh.v13.i10.1367.
The global pandemic of coronavirus disease 2019 (COVID-19) changed dramatically all priorities on medical society and created several challenges for clinicians caring for patients with liver diseases. We performed a comprehensive review about how COVID-19 can affect the liver, the influence of liver diseases on the risk of developing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and COVID-19 severity and also some strategies to overcome all the challenges clinicians have to face in the management of patients with liver diseases in a period of time when all the focus turned on COVID-19. We analyze the relationship between COVID-19 and non-alcoholic fatty liver disease, alcoholic liver disease, viral hepatitis, autoimmune liver disease, cirrhosis, hepatocellular carcinoma and liver transplantation, as well as the approach to SARS-CoV-2 vaccination.
2019年冠状病毒病(COVID-19)全球大流行极大地改变了医学领域的所有优先事项,并给照顾肝病患者的临床医生带来了诸多挑战。我们进行了一项全面综述,内容涉及COVID-19如何影响肝脏、肝病对感染严重急性呼吸综合征冠状病毒2(SARS-CoV-2)风险及COVID-19严重程度的影响,以及在所有关注点都转向COVID-19的时期,临床医生在管理肝病患者时为克服所面临的所有挑战可采取的一些策略。我们分析了COVID-19与非酒精性脂肪性肝病、酒精性肝病、病毒性肝炎、自身免疫性肝病、肝硬化、肝细胞癌及肝移植之间的关系,以及SARS-CoV-2疫苗接种方法。