Bryngelson J D, Wolynes P G
Noyes Laboratory, University of Illinois, Urbana 61801.
Proc Natl Acad Sci U S A. 1987 Nov;84(21):7524-8. doi: 10.1073/pnas.84.21.7524.
The theory of spin glasses was used to study a simple model of protein folding. The phase diagram of the model was calculated, and the results of dynamics calculations are briefly reported. The relation of these results to folding experiments, the relation of these hypotheses to previous protein folding theories, and the implication of these hypotheses for protein folding prediction schemes are discussed.
自旋玻璃理论被用于研究蛋白质折叠的一个简单模型。计算了该模型的相图，并简要报告了动力学计算结果。讨论了这些结果与折叠实验的关系、这些假设与先前蛋白质折叠理论的关系以及这些假设对蛋白质折叠预测方案的意义。
