Watanabe Noriya, Takeda Masaki
Research Center for Brain Communication, Research Institute, Kochi University of Technology, Kochi, Japan; Center for Information and Neural Networks, National Institute of Information and Communications Technology, Osaka, Japan.
Research Center for Brain Communication, Research Institute, Kochi University of Technology, Kochi, Japan.
Neurosci Res. 2022 Feb;175:53-61. doi: 10.1016/j.neures.2021.11.004. Epub 2021 Nov 18.
When an individual is faced with adversity, the brain and body work cooperatively to adapt to it. This adaptive process is termed psychological resilience, and recent studies have identified several neurophysiological factors ("neurophysiological resilience"), such as monoamines, oscillatory brain activity, hemodynamics, autonomic activity, stress hormones, and immune systems. Each factor is activated in an interactive manner during specific time windows after exposure to stress. Thus, the differences in psychological resilience levels among individuals can be characterized by differences in the temporal dynamics of neurophysiological resilience. In this review, after briefly introducing the frequently used approaches in this research field and the well-known factors of neurophysiological resilience, we summarize the temporal dynamics of neurophysiological resilience. This viewpoint clarifies an important time window, the more-than-one-hour scale, but the neurophysiological dynamics during this window remain elusive. To address this issue, we propose exploring brain-wide oscillatory activities using concurrent functional magnetic resonance imaging (fMRI) and electroencephalogram (EEG) techniques.
当一个人面临逆境时，大脑和身体会协同工作以适应它。这种适应过程被称为心理韧性，最近的研究已经确定了几种神经生理因素（“神经生理韧性”），如单胺类物质、脑振荡活动、血液动力学、自主神经活动、应激激素和免疫系统。在接触压力后的特定时间窗口内，每个因素都会以交互方式被激活。因此，个体之间心理韧性水平的差异可以通过神经生理韧性的时间动态差异来表征。在这篇综述中，在简要介绍该研究领域常用的方法和神经生理韧性的知名因素之后，我们总结了神经生理韧性的时间动态。这一观点明确了一个重要的时间窗口，即超过一小时的时间尺度，但在此窗口期间的神经生理动态仍不清楚。为了解决这个问题，我们建议使用同步功能磁共振成像（fMRI）和脑电图（EEG）技术来探索全脑振荡活动。
